Role of vitamin D and insulin resistance in polycystic ovary syndrome | ||||
| Journal of advanced Biomedical and Pharmaceutical Sciences | ||||
| Article 1, Volume 4, Issue 4, October 2021, Page 186-194 PDF (556.02 K) | ||||
| Document Type: Review Articles | ||||
| DOI: 10.21608/jabps.2021.70702.1125 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Aya Mohammed Abdallah   1; Gamal Elazab2; Mohammed Hani Mosbeh3; Hatem Sarhan4
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| 1faculty of pharmacy minia university | ||||
| 2clinical pharmacy department, faculty of pharmacy, Tanta university | ||||
| 3Obstetrics and Gynaecology department, Faculty of Medicine, Minia University | ||||
| 4Pharmaceutics Department, Faculty of Pharmacy, Minia University, Minia, Egypt | ||||
| Abstract | ||||
| Polycystic ovary syndrome (PCOS) is considered the commonest endocrinological disorder in childbearing age women with an incidence of 10%. Vitamin D has been shown in several studies to have a positive impact on female reproductive diseases, as well as PCOS. The diagnosis of PCOS, clinical symptoms, pathophysiology, hypovitaminosis D, insulin resistance, and the various methods for vitamin D and insulin assessment are all covered in this study. Androgen hypersecretion, oligo-ovulation, and/or ovarian morphologic features are used to diagnose this condition. Androgen excess, neuroendocrine causes, and insulin resistance are all part of the pathophysiology. Some female genital organs have been found to contain vitamin D receptors. Insulin regulates steroid biosynthesis in the ovaries and follicular maturation, so vitamin D is essential. | ||||
| Keywords | ||||
| 25 (OH) D; Polycystic Ovary Syndrome; Insulin resistance; Vitamin D | ||||
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