EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY
Abdel Hamid, M., Fahmy, H., Elsherif, S., Abd Elnaby, H., Ashraf, J. (2021). EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY. EKB Journal Management System, 3(4), 55-56. doi: 10.21608/alexpo.2021.96239.1272
Mowaffak Abdel Hamid; Hossam Fahmy; Sherine Elsherif; Hoda Abd Elnaby; Jailan Ashraf. "EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY". EKB Journal Management System, 3, 4, 2021, 55-56. doi: 10.21608/alexpo.2021.96239.1272
Abdel Hamid, M., Fahmy, H., Elsherif, S., Abd Elnaby, H., Ashraf, J. (2021). 'EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY', EKB Journal Management System, 3(4), pp. 55-56. doi: 10.21608/alexpo.2021.96239.1272
Abdel Hamid, M., Fahmy, H., Elsherif, S., Abd Elnaby, H., Ashraf, J. EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY. EKB Journal Management System, 2021; 3(4): 55-56. doi: 10.21608/alexpo.2021.96239.1272

EFFECTIVENESS OF LYOPHILIZED GROWTH FACTORS FOR SUBACROMIAL IMPINGEMENT: RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY

ALEXMED ePosters
Article 224, Volume 3, Issue 4, December 2021, Page 55-56  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2021.96239.1272
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Authors
Mowaffak Abdel Hamid1; Hossam Fahmy2; Sherine Elsherif1; Hoda Abd Elnaby3; Jailan Ashraf email orcid 1
1Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
2Professor of Clinical Pathology Faculty of Medicine, Ain Shams University, Cairo, Egypt.
3Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
Abstract
Introduction
Subacromial impingement syndrome (SIS) is the most commonly reported shoulder pathology that affects various aspects of patients’ daily activities. It implies the mechanical compression of rotator cuff tendons, long head of biceps and subacromial/subdeltoid bursae under the coracoacromial arch. Treatment remains controversial as implicated by its multifactorial nature and its disparate theories of pathogenesis. Recently, L-GF has proved to be an effective novel injection material. It is thus interesting to study its effect on SIS.

Methods
Sixty patients with SIS were included in the study. Patients were identified as having SIS when clinically they had anterolateral shoulder pain, a painful arc of motion and positive impingement signs. The study was double blind. Patients were randomly divided to receive either saline or L-GF injection, under ultrasonographic guidance.

Results
There was no statistically significant difference between the two groups as regards age, disease duration and gender.
The L-GF group has shown greater reduction in VAS score at follow up. There was statistically significant improvement in both active and passive internal rotation ROM in the L-GF group at follow up. Only the L-GF group has shown statistically significant improvement regarding SPADI-Disability scale as well as significant improvement in the longitudinal thickness of the supraspinatus tendon at follow up.

Conclusion
From this study it can be concluded that L-GF injection in patients with SIS has resulted in significant improvement as regards pain and disability as well as significant reduction in supraspinatus tendon thickness as measured by ultrasound compared to the saline group.
Keywords
lyophilized; growth factors; subacromial impingement
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