Potential effects of germinated legumes in dyslipidemic rats | ||||
| Egyptian Journal of Chemistry | ||||
| Article 43, Volume 65, Issue 5, May 2022, Page 435-445 PDF (718.75 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2021.90870.4352 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Fawzi Amin El-Shobaki 1; Ibrahim Hassan Badawi2; Zeinab Abdel-aal Saleh  2; Hagar Farid Elbakry 2; Maha M Soltan3; Abdel-Razik Hassan Farrag 4
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| 1Nutrition and Food Science Dept., National Research Centre, Dokki, Cairo, 12622, Egypt. | ||||
| 2Nutrition and Food Science Dept., National Research Center, Dokki, Cairo, Egypt. | ||||
| 3Chemistry of Medicinal Plants Dept., National Research Centre, Dokki, Cairo, 12622, Egypt. | ||||
| 4Pathology Dept., National Research Center | ||||
| Abstract | ||||
| Legumes have good nutritional value and are consumed by a lot of people all over the world and particularly the relatively low-income individuals. It is thus important to always try to further improve the nutritional value of these legumes using simple processing. In the present study, chickpea and soybean were soaked and germinated before involved in a diet given to animals suffering from dyslipidemia due to consumption of animal fat (Lamb fat). The generation of bioactive peptides after germination was followed by SDS PAGE. A feeding experiment was conducted where groups of albino rats were used, some were given the diet containing fat and the others were given a diet supplemented with either chickpea or soybean once non-germinated and the other germinated seeds. The produced dyslipidemia and the change in lipid parameters in all groups were biochemically and histopathologically assessed. The results proved that the deleterious effect of feeding lamb fat was corrected to a good extent when the diet contains germinated legumes. The conclusion is that germination of legumes generates bioactive peptides. This in addition to other compounds with bioactive action such as polyphenols possesses antioxidant power that helps to prevent the deleterious effect of dyslipidemia. | ||||
| Keywords | ||||
| Bioactive peptides; germination; chickpea; soybean; SDS–PAGE; dyslipidemia; histopathology | ||||
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