Provocating factors of vitiligo | ||||
Benha Journal of Applied Sciences | ||||
Article 43, Volume 6, Issue 4, August 2021, Page 279-282 PDF (409.5 K) | ||||
Document Type: Original Research Papers | ||||
DOI: 10.21608/bjas.2021.197962 | ||||
View on SCiNiTO | ||||
Authors | ||||
A.I. Eltaweel1; R.M. Salem1; A.M. Abdelrahman2; H.A. Hegazy1 | ||||
1Dermatolgoy, Venerology and Andrology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||||
2Clinical and Chemical Pathology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||||
Abstract | ||||
Vitiligo is an acquired, chronic depigmenting disorder of the skin. Although the exact cause is still under debate, the disease results from the selective loss of melanocytes, which in turn causes pigment dilution in the affected areas of the skin and/or mucosa. Melanocyte precursors can be found in the hair follicle bulge; differentiated, pigment-producing melanocytes reside in the basal layers of the epidermis and the hair matrix. Depending on the disease course, skin and hair are affected to different degrees. Clinically, skin lesions present as milky white, non-scaly patches with distinct margins. The researchers are trying to explain the pathogenesis of vitiligo with different hypotheses mainly; genetic, autoimmune, autocytotoxic, neurogenic, microenviromental,viral, apoptotic cell, adhesion disorders and multivariate theories .The most popular theory of vitiligo development is a multifactorial hypothesis according to which genetic conditions predispose vitiligo macules to occur as a result of specific environmental factors.In this study , was aimed to evaluate the provocating factors of vitiligo in vitiligo patients . | ||||
Keywords | ||||
Provocating; vitiligo | ||||
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