Office-Based Steroid Injection in Benign Vocal Fold Lesions
Baraka, M., Behairy, E., El Desouky, H., Mostafa, S., Ezzat, E. (2021). Office-Based Steroid Injection in Benign Vocal Fold Lesions. EKB Journal Management System, 22(22), 1-9. doi: 10.21608/ejentas.2021.86930.1396
Mohammad Baraka; Essam Abd-elwanees Behairy; Hossam El Desouky; Shaimaa Mostafa; Eman Ezzat. "Office-Based Steroid Injection in Benign Vocal Fold Lesions". EKB Journal Management System, 22, 22, 2021, 1-9. doi: 10.21608/ejentas.2021.86930.1396
Baraka, M., Behairy, E., El Desouky, H., Mostafa, S., Ezzat, E. (2021). 'Office-Based Steroid Injection in Benign Vocal Fold Lesions', EKB Journal Management System, 22(22), pp. 1-9. doi: 10.21608/ejentas.2021.86930.1396
Baraka, M., Behairy, E., El Desouky, H., Mostafa, S., Ezzat, E. Office-Based Steroid Injection in Benign Vocal Fold Lesions. EKB Journal Management System, 2021; 22(22): 1-9. doi: 10.21608/ejentas.2021.86930.1396

Office-Based Steroid Injection in Benign Vocal Fold Lesions

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 34, Volume 22, Issue 22, January 2021, Page 1-9  XML PDF (942.98 K)
Document Type: Original Article
DOI: 10.21608/ejentas.2021.86930.1396
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Authors
Mohammad Barakaorcid 1; Essam Abd-elwanees Behairy2; Hossam El Desouky3; Shaimaa Mostafa email orcid 4; Eman Ezzat5
1Oto Rhino Laryngology Department, Phoniatric Unit, Faculty of Medicine, Ain Shams University Egypt.
2Oto Rhino Laryngology, Faculty of Medicine, El Menoufia University, Egypt.
3Oto Rhino Laryngology Department, Phoniatric Unit, Faculty of Medicine, Cairo University, Egypt.
4Phoniatric department, Hearing and Speech Institute, Giza, Egypt
5Oto Rhino Laryngology Department, Phoniatric Unit, Faculty of Medicine, Menoufia University, Egypt.
Abstract
Background: Benign vocal fold lesions (BVFLs) are usually caused by vocal abuse or misuse. Conservative treatment and micro laryngeal surgery (MLS) are recommended in the treatment. However, conservative measures are usually difficult to perform and some patients are contraindicated for general anesthesia.
Objective: This study is designed to assess the practical application, effectiveness, and side effects of office-based steriod injection via a transnasal route.
Patients and Methods: This study included 29 patients with BVFLs. Transnasal endoscopic steroid injection (TESI) was performed via operating channel for all patients. Local anesthesia was used to inject betamethasone into Reinke's space at the base of the lesion. Acoustic analysis, including fundamental frequency (F0), jitter, shimmer, noise to a harmonic ratio (NHR), aerodynamic analysis (MPT), auditory perceptual assessment using modified GRBAS scale, videolaryngostroboscopy (VLS) evaluations, and voice handicap index (VHI), was done before and three months after TESI.
Results: Three months after injection, the VLS demonstrated that remission in size or lesions improvement was observed in 20 patients, total disappearance in 4 patients, and no improvement in 5 patients. The summation of the modified GRBAS scale also indicated highly significant improvement after TESI (P < 0.01). MPT showed a highly significant increase post-injection. VHI showed a highly significant reduction post-injection. Acoustic analysis revealed significant improvements in F0, jitter, shimmer, and NHR (P <0.05).
Conclusion : Office-based TESI is an effective, safe, easy, and feasible alternative treatment method in some BVFLs
Keywords
Benign vocal fold lesions; intralesional injection; steroids; transnasal endoscopic injection
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