Green Chemistry Approach for Efficient Synthesis of Some New Spiro [Indoline- 3,4'-Pyran] Derivatives and Prediction their Biological Activity by PASS INET | ||||
Journal of Pharmaceutical and Applied Chemistry | ||||
Volume 1, Issue 2, September 2015, Page 24-27 PDF (526.2 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12785/jpac/010201 | ||||
View on SCiNiTO | ||||
Authors | ||||
Ahmed M. M. El-Saghier1; Eman A. Ahmed1; Ahmed M. A. Mahmoud1; Fathy F. Abdel-latif2; Mohamed A. Ameen2; Omar M. Elhady3; Moumen S. Kamel2 | ||||
1Department, Faculty of Science, Sohag University, Sohag, 82524, Egypt | ||||
2Chemistry Department, Faculty of Science, Minia University, El Minia 61511, Egypt. | ||||
3Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt. | ||||
Abstract | ||||
Some new spiro compounds have been synthesized by reaction of isatin with different nucleophiles containing activemethylene compounds. Their chemical structures have been confirmed by IR, 1HNMR and by elemental analysis. | ||||
Keywords | ||||
One pot synthesis; Diammonium hydrogen phosphate; Isatin; Aqueous media; MW; PASS Inet | ||||
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