NOVEL HETEROCYCLES BASED ON 1, 3, 4-THIADIAZOLE SCAFFOLD AS INSECTICIDES | ||||
| Journal of Environmental Science | ||||
| Article 2, Volume 40, Issue 2, December 2017, Page 19-44 PDF (780.64 K) | ||||
| Document Type: Review Article | ||||
| DOI: 10.21608/jes.2017.20047 | ||||
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| Authors | ||||
| Madkour, H. F1; Azab, M. E1; Aly, A. F2; Khamees, M. S. M1 | ||||
| 1Synthetic Organic Chemistry Lab, Chemistry Department, Faculty of Science, Ain Shams University | ||||
| 2Central Agricultural Pesticide Lab., Pesticide Formulations Department, Agricultural Research Center, Dokky, Giza, Egypt. | ||||
| Abstract | ||||
| The crop plants are the major source of human nutrition, but insects and pests cause huge economic losses every year. The authors were interested in developing novel insecticidal agents with low toxicity and an acceptable impact on the environment. Thus, 2-amino-5-(substituted)-1, 3, 4-thiadiazoles (1a, b) were used as versatile materials to synthesize novel compounds through reaction with different electrophiles. The insecticidal activity of the synthesized compounds was tested using 4th instar larvae of spodoptera littoralis. Most of the tested compounds showed good to excellent insecticidal activity. Thus, the synthesized compounds could be used in the field of pest control through using them in proper pesticide formulations. | ||||
| Keywords | ||||
| : Insecticidal activity; 1; 3; 4-Thiadiazole; Thiadiazolopyrimidine; Imidazothiadiazole; Spodoptera littoralis | ||||
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