Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities
Vijayakumar, S., Vanangamudi, G., Thirunarayanan, G. (2016). Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities. EKB Journal Management System, 2(3), 51-60. doi: 10.18576/jpac/020305
S. Vijayakumar; G. Vanangamudi; G. Thirunarayanan. "Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities". EKB Journal Management System, 2, 3, 2016, 51-60. doi: 10.18576/jpac/020305
Vijayakumar, S., Vanangamudi, G., Thirunarayanan, G. (2016). 'Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities', EKB Journal Management System, 2(3), pp. 51-60. doi: 10.18576/jpac/020305
Vijayakumar, S., Vanangamudi, G., Thirunarayanan, G. Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities. EKB Journal Management System, 2016; 2(3): 51-60. doi: 10.18576/jpac/020305

Preheated Fly-Ash as Catalyst for the Synthesis of Chalcones under Microwave Irradiation, Correlation Studies and Anti-Microbial Activities

Journal of Pharmaceutical and Applied Chemistry
Volume 2, Issue 3, September 2016, Page 51-60  XML PDF (577.48 K)
Document Type: Original Article
DOI: 10.18576/jpac/020305
View on SCiNiTO View on SCiNiTO
Authors
S. Vijayakumar1; G. Vanangamudi1; G. Thirunarayanan2
1PG and Research Department of Chemistry, Government Arts College, C-Mutlur-608 102, India.
2Department of Chemistry, Annamalai University, Annamalainagar-608 002, India.
Abstract
A series of 2, 6-dimethoxyphenyl chalcones have been synthesized by Crossed-Aldol condensation of 2, 6-dimethoxyacetophenone and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, and NMR spectral data. The spectral data of these chalcones have been correlated with Hammett substituents constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies has been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby disc diffusion method.

Keywords
Substituted styryl 2, 6-dimethoxyphenyl ketones; UV spectra, IR spectra, NMR spectra, Substituent effects, Antimicrobial activities
Statistics
Article View: 54
PDF Download: 64