Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation | ||||
| International Journal of Medical Arts | ||||
| Article 8, Volume 3, Issue 4, October 2021, Page 1811-1817 PDF (1.32 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2021.200543 | ||||
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| Authors | ||||
Ahmed Bedeir Abd El Salam  1; Faisal Ali Mustafa 2; Zainab Shehata Sayed 3; Hamada Mohamed Abuelmatti 4
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| 1Department of Radiology, Damietta Faculty of Medicine, Al-Azhar University, Egypt | ||||
| 2Department of Obstetrics and Gynecology, Faculty of Medicine, Al- Azhar University, Assiut, EGYPT | ||||
| 3Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt | ||||
| 4Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt | ||||
| Abstract | ||||
| Background: Midline cerebral structures are essential for the normal morphogenesis and function of the fetal brain. However, the diagnosis of congenital anomalies of midline cerebral structures. The Aim of The Work: This study aimed to evaluate the role of 2D versus 4D ultrasound in the diagnosis of midline structures of the fetal brain at the second trimester of pregnancy. Patients and Methods: 200 pregnant women at the second trimester [18-22 weeks] were selected. They were clinically evaluated to check the female and fetal wellbeing. Then a screening of fetal brain midline strictures had been performed by two- and four-dimensional ultrasound, aiming to discover any anomalies of the fetal brain midline structure. Both scans were compared with the postnatal transcranial ultrasound. Results: The 2D ultrasound detected no abnormality in 194 out of 200 fetuses [97.0%], and 4 cases [2.0%] had mega-cisterna magna, and 2 cases [1.0%] had encephalomylocele, which were detected by the 4 D and confirmed by postnatal transcranial ultrasound. The 4 D US discovered 2 cases [1.0%] of Dandywalker malformation, which was confirmed by postnatal transcranial US. There was a complete agreement between prenatal 4D ultrasound and postnatal transcranial ultrasound. The prenatal 2D ultrasound had a sensitivity of 75.0%, specificity of 100.0%, PPV of 100.0%, NPV of 98.7% and overall accuracy of 99.0%. Otherwise, the prenatal 4D ultrasound was 100.0% sensitive and specific. Conclusion: 4D ultrasound showed superiority in the diagnosis and confirmation of the fetal brain midline structure’s abnormalities. Also, the prenatal 4D ultrasound was 100.0% sensitive as postnatal transcranial US. | ||||
| Keywords | ||||
| Two-Dimensional; Four-Dimensional; Fetal Brain Midline Structures; Postnatal; Transcranial Ultrasound | ||||
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