Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient
Adeyanju, O., Ewaoche, E., Plavec, J. (2017). Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient. EKB Journal Management System, 3(2), 8-13. doi: 10.18576/jpac/030303
O. Adeyanju; E. A. Ewaoche; J. Plavec. "Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient". EKB Journal Management System, 3, 2, 2017, 8-13. doi: 10.18576/jpac/030303
Adeyanju, O., Ewaoche, E., Plavec, J. (2017). 'Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient', EKB Journal Management System, 3(2), pp. 8-13. doi: 10.18576/jpac/030303
Adeyanju, O., Ewaoche, E., Plavec, J. Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient. EKB Journal Management System, 2017; 3(2): 8-13. doi: 10.18576/jpac/030303

Effect of Chemical Modification by Oxidation on The Physicochemical Properties of Sweitenia mycrophylla Gum. A Potential Excipient

Journal of Pharmaceutical and Applied Chemistry
Volume 3, Issue 2, September 2017, Page 8-13  XML PDF (501.77 K)
Document Type: Original Article
DOI: 10.18576/jpac/030303
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Authors
O. Adeyanju1; E. A. Ewaoche2; J. Plavec3
1Department of Chemistry, Faculty of Natural Sciences, University of Jos, Nigeria.
2Department of Pharmaceutical technology, Faculty of Pharmaceutical Sciences, University of Jos, Nigeria.
3National Institute of Chemistry, NMR Centre, Ljublijana, Slovenia.
Abstract
Oxidized S.mycrophylla gum was prepared,characterized by FTIR, XRD, SEM, EDX and evaluated for its physicochemical characteristics. Oxidized gum showed improved physicochemical parameters, than the native gum with moisture content to be 3.5±40.10%. Ash 1.98±0.25%, protein 1.04 ± 0.05%, pH 4.95± 0.25, viscosity (CS), 56.32±6.79, refractive index 1.33±0.02, water holding capacity 94:63 ±8.45%, specific rotation - 15.2±0.09 degree Celsius,Emulsifying capacity 48.03±4.65cm-1 and swelling index 25.36±2.64%. Chemical modification via oxidation increased the physicochemical properties of the native gum. The experimental work, provide enough evidence to exploit this natural biopolymer in food and pharmaceutical formulations..

Keywords
Carboxyl group; Sweitenia mycrophylla gum; FTIR; XRD; SEM
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