Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application
Azadi, M., Shams Ghahfarokhi, Z., Teimouri, A. (2017). Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application. EKB Journal Management System, 3(2), 88-93. doi: 10.18576/jpac/030308
Mohammad Azadi; Zahra Shams Ghahfarokhi; Abbas Teimouri. "Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application". EKB Journal Management System, 3, 2, 2017, 88-93. doi: 10.18576/jpac/030308
Azadi, M., Shams Ghahfarokhi, Z., Teimouri, A. (2017). 'Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application', EKB Journal Management System, 3(2), pp. 88-93. doi: 10.18576/jpac/030308
Azadi, M., Shams Ghahfarokhi, Z., Teimouri, A. Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application. EKB Journal Management System, 2017; 3(2): 88-93. doi: 10.18576/jpac/030308

Modification of Silk Fibroin and Gelatin-Chondroitin Sulfate Matrix with the Addition of Nanohydroxyapatite by Freeze-Drying Method for Tissue Engineering Application

Journal of Pharmaceutical and Applied Chemistry
Volume 3, Issue 2, September 2017, Page 88-93  XML PDF (834.43 K)
Document Type: Original Article
DOI: 10.18576/jpac/030308
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Authors
Mohammad Azadi1; Zahra Shams Ghahfarokhi2; Abbas Teimouri1
1Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran.
2University of Birjand, Birjand, I. R. of Iran.
Abstract
Silk fibroin/gelatin-chondroitin sulfate/nanohydroxyapatite (SF/GE-CS/nHAp) composite scaffolds were prepared by freeze-drying approach. The prepared samples were investigated using BET, FTIR, SEM, and XRD studies. In addition, the investigation of the cell proliferation, adhesion and viability using MTT, DMEM solution, and mouse preosteoblast cell confirmed the cytocompatible nature of the composite scaffolds. These results showed that this composite could be a potential candidate for tissue engineering application.

Keywords
 Chondroitin sulfate; Nanohydroxyapatite; Nanocomposite scaffolds; Gelatin; Silk fibroin; Tissue engineering
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