Some Physical Parameters of PEG-modified Magnetite Nanofluids | ||||
Journal of Pharmaceutical and Applied Chemistry | ||||
Volume 2, Issue 2, May 2016, Page 62-66 PDF (412.73 K) | ||||
Document Type: Original Article | ||||
DOI: 10.18576/jpac/020201 | ||||
View on SCiNiTO | ||||
Authors | ||||
J. Markhulia1; V. Mikelashvili1; Sh. Kekutia1; L. Saneblidze1; Z. Jabua2; D. Daraselia3; D. Jafaridze3 | ||||
1Vladimir Chavchanidze Institute of Cybernetics of the Georgian Technical University Sandro Euli str. 5, Tbilisi 0186, Georgia | ||||
2Georgian Technical University, Kostava str. 77, Tbilisi, 0175, Georgia. | ||||
3Tbilisi state university, 1, Chavchavdze Ave., 0179 Tbilisi, Georgia. | ||||
Abstract | ||||
The development of the synthesis of stable aqueous suspensions of superparamagnetic iron oxide nanoparticles stabilized with unmodified polyethylene glycol (PEG) at two molecular weights (4000 and 6000 Da) and several PEG/iron ratios has been reported. The obtained biocompatible polymer (PEG) coated nanoparticle dispersive solution with pH ≈ 6.5 and solid phase content ranging from 0.02-0.75 % w/v has been investigated for optical and magnetic properties. Biomedical application requires the biocompatible superparamagnetic iron oxide nanoparticles (SPION), which are stable and well dispersed in water at physiological pH or in physiological salinity. Biocompatible 10-20 nm sized SPIONs have been synthesized via co-precipitation method in the vacuum environment. These SPIONs have been modified with PEG in one-pot synthesis. Vibrating Sample Magnetometer (VSM) studies show the effect of phase transformations on the magnetic properties of the nanoparticles and surfactant influence on the characteristic of the magnetization at room temperatures into high and low magnetic fields. | ||||
Keywords | ||||
Magnetic nanofluid; SPION; Biocompatible nanoparticles; Core/shell magnetic nanoparticles | ||||
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