The Diversity of Bacteriocin and Its Antiviral Potential: An Overview | ||||
| Egyptian Journal of Medical Microbiology | ||||
| Article 22, Volume 30, Issue 4, October 2021, Page 175-180 PDF (197.68 K) | ||||
| Document Type: Review articles | ||||
| DOI: 10.21608/ejmm.2021.203649 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Nehal Mohamed Elalem  1; Riham M. Shawky2; Rehab Bahy3; Abeer A.H. Boselia1; Mohamed Emara2
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| 1Department of Microbiology, Egyptian Drug (EDA), Formerly National organization for Drug Control and Research (NODCAR), Giza,12611,Egypt | ||||
| 2Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Cairo, Egypt | ||||
| 3Department of Microbiology and Immunology, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt | ||||
| Abstract | ||||
| The viral resistances to the known antiviral agent have raised the need for developing alternatives antiviral agents.one of the promising alternatives are bacteriocins. Bacteriocin are natural peptides ribosomal synthesized by gram negative and gram positive bacteria. Bacteriocins are secreted as a method for the producer to compete in the environment. Bacteriocin gene cluster can be found on plasmid or chromosome. Bacteriocins have presented wide range of activity against bacteria, fungi, virus and cancer cells and have a high margin of safety which encouraged its use in food and pharmaceutical applications. Nisin is one example of bacteriocins approved by FDA for use as food preservative. Bacteriocin nature variation is one of its unique qualities. Bacteriocin varies in physical, chemical, molecular and genetic nature. This variation have been studied and recoded over the years. In this review we discuss and summarized the diversity of bacteriocins and their different mechanism of actions against virus. | ||||
| Keywords | ||||
| Acteriocin; Antiviral; Antimicrobial | ||||
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