Comparison between clinical and biochemical versus interleukin 28B as a predictive factor of virological response to direct antiviral drugs without interferone in treatment of hepatitis C virus patients | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 30, Volume 73, Issue 10, October 2018, Page 7842-7849 PDF (543.09 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2018.20458 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mahmoud Mohammad Moussa Bazeed; Anwar Gomaa Elsheety; Mohammad Saied Bakeer; Mohamed Ali Saber; Essam Abdel Nabi Mohammady 
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| Department of Internal Medicine, Faculty of Medicine, Al-Azhar University | ||||
| Abstract | ||||
| Introduction: for SNP, the CC is associated with a higher SVR after DAAs/RBV therapy while, the genotype TT is a risk factor for non-response. Aim of the work: this study aimed to assess the value of SNP (rs8o99917) as a predictor of SVR. Methodology: this study was a retrospective controlled study and was performed on a total number of 15o patients who were treated by DAAs/RBV for 12 weeks and SNP was done for the all the patients. Results: CC genotype was more prevalent in SVR group than CT and TT genotypes. Conclusion: determination of SNP before starting antiviral therapy may serve as a good response predictor. | ||||
| Keywords | ||||
| HCV-direct acting antiviral drugs; interleukin 28b SNP | ||||
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