Enhanced Antioxidant Activity of Di- and Triorganotin Complexes Derived from Mefenamic Acid | ||||
| Egyptian Journal of Chemistry | ||||
| Article 47, Volume 65, Issue 5, May 2022, Page 483-490 PDF (309.89 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2021.82292.4056 | ||||
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| Authors | ||||
Dhekra Jawad Hashim1; Tamara f Falah2; Angham G. Hadi   3
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| 1Technical Institute of Babylon ,Al-Furat Al-Awsat Technical University, Babylon, Iraq | ||||
| 2Department of Engineering Medical Device Technologies , Hilla university college , Babylon , Iraq | ||||
| 3Chemistry department/ College of science/ University of Babylon | ||||
| Abstract | ||||
| Organotin(IV) compounds have gained significant interest in both the chemical and pharmaceutical industry. This research concentrates on synthesis of di and tri-organotin complexes with mefenamic acid and characterized with different techniques such as elemental analysis, FTIR, proton and carbon NMR. The anti-oxidant properties of the complexes were assessed using the 1,1-diphenyl-2-picrylhydrazyl, DPPH and CUPRAC Method . The complexes' scavenging activities were assessed and compared to those of the free drug. The synthesized complexes gives higher antioxidant activity than free drug, also, complex 3 of di methyltin-mefenamic was the highest as compared with the other complexes. | ||||
| Keywords | ||||
| Antioxidant activities; Organotin(IV); Carboxylates; DPPH; Antitumor; Triorganotin(IV); Diorganotin(IV) | ||||
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