Effect of brown algae ethanolic extract consumption on obesity complications induced by high fat diets in rats | ||||
| مجلة کلية التربية النوعية - جامعة بورسعيد | ||||
| Article 22, Volume 17, Issue 18, June 2022 | ||||
| Document Type: المقالة الأصلية | ||||
| DOI: 10.21608/pssrj.2021.98769.1148 | ||||
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| Authors | ||||
يوسف عبد العزيز الحسانين 1; ساره أحمد محمود فايز فايز  2; صفاء على الوصيف3; سارة أحمد محمد سيد احمد 4
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| 1کلية الاقتصاد المنزلى - جامعة المنوفية | ||||
| 2کلية تربيه نوعيه قسم اقتصاد منزلي (تغذية وعلوم اطعمة) | ||||
| 3قسم الاقتصاد المنزلى، کلية التربية النوعية، جامعة بوزرسعيد | ||||
| 4مدرس بقسم الاقتصاد المنزلي کلية التربيه النوعيه -جامعة بور سعيد.مصر | ||||
| Abstract | ||||
| The study was designed to investigate the effect of brown algae (Sargassum subrepandum) ethanolic extract on obesity and is complications induced by high fat diet in rats.Thirty six rats were divided into two main groups, the first group (Group 1, 6 rats) still fed on basal diet and the other main group (30 rats) was with high fat diet (HFD) for 8 weeks which classified as follow: group (2), fed on HFD as a positive control; group (3), fed on HFD containing 0.25 % BAE; group (4), fed on HFD containing 0.50 % BAE; group (5), fed on HFD containing 0.75 % BAE and group (6), fed on HFD containing 1.0 % BAE. At the end of the experiment, rats of normal group increase in its amount by 90.11% when compared to the base line. Rats of the obese group increased by the rate of 147.02% when compared to the base line. Also, addition of 0.25, 0.50, 0.75 to 1.00% of BAE induced significant (p≤0.05) decreasing on body weight of the obese rats when compared to the starting point of the experiment. Also, BAE was effective in protecting against obese complications including lower the serum glucose level, inhibithepatotoxicity through liver serum enzymes-lowering activity, improvement of the serum immunological parameters and decreasing rate on the formation of MDA in serum, in evidence of lipid peroxidation and oxidative stress. In conclusion, we recommended like of that algae extracts by a concentrations ranged 0.25-1.0 % amount to be included in our daily diets | ||||
| Keywords | ||||
| Brown algae; obesity; serum glucose; hepatotoxicity | ||||
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