A New Tool Against Anopheles Gambiae 4th Instar Larvae; Ocimum basilicum Mediated Silver Nanoparticles | ||||
Egyptian Academic Journal of Biological Sciences, E. Medical Entomology & Parasitology | ||||
Article 2, Volume 13, Issue 2, December 2021, Page 11-20 PDF (930.53 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/eajbse.2021.206885 | ||||
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Authors | ||||
Ntoumba Agnes Antoinette1; Sikapi Fouda Jean Yves2; Akeumbiwo Tchumkam Cedric2; Mepoubong Kengne Nelie Alida3; Wolfgang Eyisap Ekoko4; Gisele Etame Loe2; Eya’ane Meva Francois3; Leopold Gustave Lehman1 | ||||
1Department of Animal Biology and Physiology, Faculty of Science, The University of Douala, Douala, Cameroon. | ||||
2Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon | ||||
3Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon. | ||||
4Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), Yaoundé, Cameroon | ||||
Abstract | ||||
The excessive use or spillage of chemical insecticides is harmful to the environment and living organisms. Their replacement with plant-based insecticides is a cheap, and an excellent alternative to combat vector-borne diseases. Ocimum basilicum, commonly known as Sweet Basil, belongs to the genus Ocimum of the family Lamiaceae. Various species of Ocimum are known for their peculiar strong odours and culinary appreciation. This study presents the toxicity of silver nanoparticles obtained from an aqueous extract of Ocimum basilicum on the early 4th instar larvae of Anopheles gambiae, the main vector of malaria in Sub-Saharan Africa. The nanoparticles were characterised by ultraviolet-visible spectroscopy for their formation, infrared spectroscopy for the interface metabolites-silver and X-ray powder diffraction for their nature. The silver nanoparticles based on Ocimum basilicum are water dispersible, stable, pure and functionalized by the plant secondary metabolites and thus, they represent a new means for Anopheles gambiae vector control. | ||||
Keywords | ||||
Malaria; Anopheles gambiae; Ocimum basilicum; silver nanoparticles; insecticide | ||||
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