ANTI-OXIDANT AND ANTI-BACTERIAL ACTIVITIES OF SINAPIS ALBA L. (LEAVES, FLOWERS AND FRUITS) GROWN IN SYRIA | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 6, Volume 44, Issue 2, December 2021, Page 339-346 PDF (606.75 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.2021.207153 | ||||
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| Authors | ||||
| Racha Khatib; Kinan Al-Makky* | ||||
| Department of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Damascus University, Damascus, Syria | ||||
| Abstract | ||||
| This research aims to determine the phenolic and flavonoid contents in the extracts of the Sinapis alba L. parts and to calculate the free radical scavenging and antibacterial activity of them. The highest phenolic content was 28.302 mg/g dry plant, the highest flavonoid content was 2.072 mg/g dry plant in the methanolic flower extract. In interaction with diphenyl picryl hydrazyl, the inhibitory concentrations of half of free radicals ranged from 2.836 mg/mL in the methanolic fruit extract to 17.853 mg/mL in the chloroform flower extract. Methanolic extracts showed a zone of inhibition against Staphylococcus aureus, the diameters of the inhibition zone were 17.2 mm in leaf and fruit extracts, and 15 mm in flower extract at a concentration of 700 mg/mL. The study showed that the methanolic extracts of Sinapis alba L. have good phenolic and flavonoid contents, good free radical scavenging activity and have antibacterial activity against Staphylococcus aureus. | ||||
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