EVALUATION OF TOTAL PHENOLIC CONTENT, TOTAL FLAVONOIDS CONTENT AND FREE RADICAL SCAVENGING ACTIVITY OF LEPIDIUM SATIVUM L. SEEDS AND LEAVES PLANTED IN SYRIA | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 9, Volume 44, Issue 2, December 2021, Page 377-385 PDF (719.3 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.2021.207156 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Najwa Mohanad Sultan* ; Racha Katib | ||||
| Department of Pharmacognosy, Faculty of Pharmacy, Damascus University, Damascus, Syria | ||||
| Abstract | ||||
| Most of previous research has focused on the seeds of Lepidium sativum L., whereas few ones were interested in the chemical content of its leaves. This research study determines total phenolic content, total flavonoids content in the methanolic and chloroformic extracts for the seeds and leaves of Lepidium sativum. Antioxidant activity of the previous extracts has also been evaluated by determining free radicals (DPPPH assay) scavenging activity. The results have shown that the methanolic and chloroformic extracts from seeds has phenolic content about (1043± 0.16mg GAE\100g) and (306.12± 0.12mg GAE\100g) respectively. Whereas, lower quantities were found in leaves (993.40± 0.16 mg GAE\100g) and (85.86± 0.01mg GAE\100g) for methanolic and chloroformic extracts respectively. However, the flavonoids content in leaves (153.32± 0.60 mg QE\100g, 70.94± 0.71mg QE\100g) was higher than in seeds (28.76 ± 0.01 mg QE\1oog ,8.38± 0.12mg QE\100g). Also, the free radicals scavenging was found to be (IC50=126.44±0.63μg\ml methanol) and (IC50=50.97±0.14μg\ml methanol) for leaves and seeds respectively. According to the results above, Lepidium Sativum can be considered as natural antioxidant and important nutritional supplements. | ||||
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