Clinico-Pathological Measures and Management of Mucinous Ovarian Cancer: Single Institutional Study | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 115, Volume 85, Issue 2, October 2021, Page 4143-4148 PDF (513.1 K) | ||||
| DOI: 10.21608/ejhm.2021.207271 | ||||
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| Authors | ||||
Mohamed Ayaty  ; Islam A Mansour
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| Abstract | ||||
| Background: Mucinous ovarian cancer is less common and less aggressive epithelial ovarian cancer, which represents 3% of epithelial ovarian cancer. Patient and methods: A retrospective descriptive analysis involving all patients with mucinous ovarian cancer who underwent surgical management or referred to National Cancer Institute (NCI), Cairo University (CU), from January 2010 to January 2020. Of 46 cases reviewed. 16 cases were excluded (10 cases had metastatic and 6 cases had incomplete data). Results: forty-six cases reviewed with median age of 48.3±18.1 years. Half of patients were in premenopausal status. Patients presented with distention with or without pain were 70% of cases, 10% of patients with abdominal mass and 6.7% of patients with bleeding. Most of cases 63.30% were diagnosed at late stages (1C and beyond). Patients had unilateral disease were 70% of cases and had elevated tumor markers were 53.3 % of cases. The most commonly elevated tumor marker was CA 125 (26.7%). Patients had comorbidities were 30% of cases. Surgery was the main line of management. Total abdominal hysterectomy and bilateral salpingo-oophorectomy plus infracolic omentectomy were done in 73.3% of patients, 6.7% underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy, 3.3% underwent cytoreductive surgery and 3.3% underwent cytoreductive surgery and 13% of patients underwent fertility sparing surgery. The role of pelvic lymphadenectomy was limited (13.3% underwent pelvic lymphadenectomy and only one patient had positive lymph node metastasis). Conclusion: The most important prognostic factors were disease stage, laterality, tumor markers and performance status. | ||||
| Keywords | ||||
| Mucinous ovarian cancer (mEOC); Surgery | ||||
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