Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria
Gamaleldin, N., Shokeir, N., Abdelaziz, H., Elweshahy, H. (2022). Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria. EKB Journal Management System, 25(1), 42-56. doi: 10.21608/scumj.2022.207565
Nahla Gamaleldin; Nagwa Shokeir; Hend H Abdelaziz; Heba Elweshahy. "Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria". EKB Journal Management System, 25, 1, 2022, 42-56. doi: 10.21608/scumj.2022.207565
Gamaleldin, N., Shokeir, N., Abdelaziz, H., Elweshahy, H. (2022). 'Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria', EKB Journal Management System, 25(1), pp. 42-56. doi: 10.21608/scumj.2022.207565
Gamaleldin, N., Shokeir, N., Abdelaziz, H., Elweshahy, H. Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria. EKB Journal Management System, 2022; 25(1): 42-56. doi: 10.21608/scumj.2022.207565

Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria

Suez Canal University Medical Journal
Article 5, Volume 25, Issue 1, March 2022, Page 42-56  XML PDF (416.72 K)
Document Type: Original Article
DOI: 10.21608/scumj.2022.207565
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Authors
Nahla Gamaleldin email orcid 1; Nagwa Shokeir1; Hend H Abdelaziz2; Heba Elweshahy1
1Department of Community Medicine, Faculty of Medicine, University of Alexandria, Egypt
2Department of Family Medicine, Ministry of Health, Egypt
Abstract
Background: Hepatitis C virus (HCV) infection is a worldwide public health problem, affecting about 3% of the world’s population. The introduction of sofosbuvir (Sovaldi) markedly changed therapeutic outcomes. The assessment of HRQoL in HCV patients under treatment might help to better understand the effect of treatment on the patient’s quality of life. Aim: The study was conducted to assess the quality of life of chronic hepatitis C patients receiving Sovaldi at the outpatient hepatology clinic in Sharq Almadina hospital. Patients and Methods: A cross-sectional survey was conducted among chronic hepatitis C patients receiving Sovaldi treatment regimen for at least 3 months. Data was collected from the studied CHCV patients using face-to-face interviews including personal & sociodemographic characteristics, The chronic liver disease questionnaire (CLDQ) to assess health-related quality of life, and the translated Arabic version of the short-form (SF 36) generic quality of life questionnaire. In addition, reviewing the medical records of studied CHCV patients to collect data about their laboratory findings was done. Results:More than two-thirds of studied patients (69.1%) discovered the disease during the National Egyptian Campaign. The overall median value of SF-36Q items was 53.19 indicating a poor HRQoL. There were significant positive correlations between the majority of SF-36Q individual domain scores and that for CLDQ P Conclusions: There were significant positive correlations between the majority of SF-36Q individual domain scores and that for CLDQ as well as the total scores.
Keywords
HCV; Sovaldi; Qol
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