Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile
M. Hamdy et al., S. (2021). Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile. EKB Journal Management System, 25(5), 1001-1016. doi: 10.21608/ejabf.2021.208200
Soha M. Hamdy et al.. "Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile". EKB Journal Management System, 25, 5, 2021, 1001-1016. doi: 10.21608/ejabf.2021.208200
M. Hamdy et al., S. (2021). 'Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile', EKB Journal Management System, 25(5), pp. 1001-1016. doi: 10.21608/ejabf.2021.208200
M. Hamdy et al., S. Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile. EKB Journal Management System, 2021; 25(5): 1001-1016. doi: 10.21608/ejabf.2021.208200

Evaluation of Insulin-like growth factor-1 (IGF-1), antioxidant enzymes, and heavy metals in Oreochromis niloticus collected from different stations along the River Nile

Egyptian Journal of Aquatic Biology and Fisheries
Article 58, Volume 25, Issue 5, September and October 2021, Page 1001-1016  XML PDF (583.36 K)
Document Type: Original Article
DOI: 10.21608/ejabf.2021.208200
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Author
Soha M. Hamdy et al.
Abstract
This study was carried out to assess the insulin-like growth factor-1 (IGF-1), levels of some physicochemical parameters and heavy metals in water collected from the River Nile. The results showed that the physicochemical concentrations of the water samples were as follows: temperature 16.3-36.5°C, transparency 54.3-80.2 cm, electrical conductivity 268-320 μS/cm, pH 7.5-8.3, dissolved oxygen 7.3-11.2 mg/l, biochemical oxygen demand 1.3-3.3 mg/l, chemical oxygen demand 6.3-10.7 mg/l, and ionized ammonia 0.57-0.96 mg/l. Heavy metals (Fe, Mn, Cu, Zn, and Pb) in water showed maximum values as follows: (5.8, 0.51, 0.350, 0.230 and 0.90 mg/l) and (5.2, 0.42, 0.13, 0.47, and 0.27 mg/l) in summer and winter, respectively. The levels of metals detected in the tilapia muscle were higher than those found in water. Increased activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) was detected in the blood analysis of O. niloticus. Levels of urea, uric acid, glucose, cholesterol and insulin-like growth factor-1 (IGF-1) were high in fish collected from polluted sites (iron and steel factory at Helwan, sugar cane factory at El-Hawamdia, Road El-Farag, and Electricity station at Shobra El-khima). In addition, a significant increase (P<0.05) was shown in the activities of catalase (CAT), superoxide dismutase (SOD), and level of malondialdehyde (MDA) when compared to reference station (V) EL-Qanater. The results indicate that Nile tilapia resisted oxidative stress induced by heavy metal exposure by antioxidant mechanisms.
Keywords
Nile tilapia; IGF-1; Antioxidant activity; Heavy metals
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