In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria | ||||
| Journal of High Institute of Public Health | ||||
| Article 2, Volume 39, Issue 3, July 2009, Page 432-448 PDF (610.62 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jhiph.2009.20845 | ||||
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| Authors | ||||
| Khouloud Barakat* 1; Hermine Tadros2 | ||||
| 1Marine Microbiology Lab., Division of Marine Environment, National Institute of Oceanography & Fisheries, Alexandria, Egypt | ||||
| 2Marine Chemistry Lab., Division of Marine Environment, National Institute of Oceanography & Fisheries, Alexandria, Egypt | ||||
| Abstract | ||||
| In vitro screening using methanolic extracts of different marine algae and one sea grass showed antibacterial activity against eight virulent strains of fish and human pathogens. 1:1 (V: V) ratios of each methanolic extract were mutually added to give 21 interactions. The interaction between Udotea sp and Codium fragile extracts exhibited higher activities against Edwardsiella tarda (18±0.9mm), Vibrio ordalli (16±0.8mm), Klebsiella pneumonia (20±1mm) and Pseudomonas aeruginosa (16±0.8mm). The bioactivity of this interaction was found to be more effective than that obtained from some common antibiotics including: Lincolin, Streptomycin and Gentamycin. The chemical constituents of these two algal extracts and their interaction were characterized using thin layer chromatography and gas chromatographic – mass spectral analysis. The bioactivity of the separated compounds was estimated. Palmitic acid was the most active fatty acid. | ||||
| Keywords | ||||
| Algal extract interactions; Pathogenic bacteria; Antibacterial activity; Gas chromatography–Mass spectrum | ||||
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