Comparison of Post-Operative Analgesic Effects of Peritonsillar Infiltration of Dexmedetomidine, Lidocaine or Both in Children Following Tonsillectomy | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 142, Volume 85, Issue 2, October 2021, Page 4308-4313 PDF (561.38 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2021.209421 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
hazem moawad weheba   ; Mohamed Mahmoud El Madany; Mohamed Aly Eloraby
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| department of anesthesia, faculty of medicine, Mansoura university, Egypt | ||||
| Abstract | ||||
| Background: Peritonsillar infiltration of local anesthetics has efficient pain relief in children undergoing tonsillectomy. We hypothesize that lidocaine plus dexmedetomidine will potentiate the analgesic effect of each other rather than. Objectives: This study aimed to compare the analgesic effect of peritonsillar infiltration of lidocaine, dexmedetomidine, or lidocaine/dexmedetomidine on post-tonsillectomy pain. The primary outcome is the time of analgesia. The secondary outcomes are postoperative pain score, the effect of study medications on postoperative hemodynamic, and complications. Patients and Methods: Ninety patients were randomly allocated to three groups, 30 patients each. L group, patients received 2mg/kg lidocaine. D group, patients received 1 μg/kg of dexmedetomidine. LD group, patients received 1 μg/kg of dexmedetomidine plus 2 mg/kg lidocaine. Results: The time of the first analgesia request (h.) was longer in the LD group (13.70 ± 2.91) when compared with the L and D groups. Postoperative pain score was significantly lower in LD and D groups compared with the L group (P <0.05) On the other hand, there was a significantly lower median VAS score in the LD group when compared with the D group (P1 <0.05) Postoperative paracetamol consumption was significantly lower in LD group (0.55 ± 0.51 gm/24h) when compared with D and L groups (0.65 ± 0.59, 2.25 ± 0.44 gm/24h respectively). Conclusion: the use of lidocaine with dexmedetomidine is better than using each drug alone in decreasing post-tonsillectomy pain and increasing the time to first request for analgesia with no significant postoperative side effects. | ||||
| Keywords | ||||
| Posttonsillectomy pain; Lidocaine; Dexmedetomidine | ||||
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