EFFICACY OF FECAL CALPROTECTIN AS A MARKER FOR THE PATHOGENICITY OF BLASTOCYSTIS HOMINIS | ||||
| Journal of the Egyptian Society of Parasitology | ||||
| Article 24, Volume 51, Issue 3, December 2021, Page 641-646 PDF (1019.38 K) | ||||
| DOI: 10.21608/jesp.2021.210455 | ||||
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| Authors | ||||
| AMIRA RAAFAT; IMAN R. ABDEL-SHAFI; MOUSA A. M. ISMAIL; NOHA M. AMIN | ||||
| Department of Medical Parasitology, Faculty of Medicine, Cairo University, Cairo, Egypt | ||||
| Abstract | ||||
| Fecal calprotectin (f-CP) is a marker of inflammation in intestine, calprotectin is released by whilte blood cells, macrophages, and epithelial cells. This study used the f-CP level as a factor to determine the pathogenicity of Blastocystis hominis. The f-CP levels were measured in Blastocystis hominis patients as compared to negative B. hominis ones with gastrointestinal symptoms related to healthy controls. A total of 235 stool samples were divided into three groups. G1: 88 stool samples of patients with gastrointestinal complaints positive only for blastocysts hominis. G2: 75 stool samples of patients with gastrointestinal complains and B. hominis free. G3: 72 stool samples of healthy volunteers, with neither gastrointestinal symptoms nor microbiological infection. The levels of f-CP were determined by specific ELISA showed that the f-CP concentration was highest in G1 & G2 as compared separately with G3, with significant differences (P < 0.001), but without significant difference between G1 & G2 (p =0.453). | ||||
| Keywords | ||||
| Blastocystis hominis; Fecal calprotectin; Gastrointestinal symptoms | ||||
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