The Antibacterial Activity of some Red Sea Soft Corals species | ||||
Egyptian Journal of Aquatic Biology and Fisheries | ||||
Article 2, Volume 16, Issue 2, May 2012, Page 13-26 PDF (916.89 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejabf.2012.2121 | ||||
View on SCiNiTO | ||||
Authors | ||||
Hassan Ibrahim1; Saad Mohamed2; Aml Farhat3; Mohamed Abu El-Regal4 | ||||
1Microbiology Lab., National Institute of Oceanography and Fisheries, Alexandria Branch | ||||
2Marine Biology Department, Faculty of Science, Suez Canal University. | ||||
3Marine Environment Division, National Institute of Oceanography & Fisheries, Hurghada branch. | ||||
4Marine Science Department, Faculty of Science, Port Said University. | ||||
Abstract | ||||
The present study aimed to investigate the antibacterial properties of crude extracts from some soft coral species from the Red Sea, Hurghada, Egypt. Crude extracts of Lobophytum pauciliforum, Dendronephthya hemprichi, Sarcophyton gracile, Sarcophyton glaucum, Sinularia gardineiri, Sinularia leptoclados, Nephthea pacifica, Sarcophyton acutum, Sarcophyton spongosium and Xenia macrospiculata, were tested against fish and human pathogenic bacteria. The well cut - diffusion technique was used to determine the absolute activity units (AU) and the minimal inhibitory concentrations (MICs) using disc-diffusion technique were determined against the most affected bacterial pathogens (E. coli and S. aureus). The AU of the ethanolic crude extract ranged from 1.4 to 25.0 for Sarcophyton acutum and Lobophytum pauciliforum, respectively. On the other side, ethyl acetate crude extracts showed the highest AU (16.0) for L. pauciliforum against S. aeurus, followed by (11.1) of N. pacifica and X. macrospiculata against). The MIC of L. pauciliforum ethyl acetate crude extract was recorded as (50 mg ml-1) against both E. coli and S. areaus ATCC 6358. Extracts from some soft corals showed the ability to inhibit the growth of some pathogenic bacteria indicating that it could be used for medical purposes. | ||||
Keywords | ||||
Antibacterial activity; Soft corals; MIC; Cytotoxicity. INTRODUCTION | ||||
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