Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma | ||||
Egyptian Journal of Neck Surgery and Otorhinolaryngology | ||||
Article 3, Volume 7, Issue 3, December 2021, Page 19-28 PDF (667.42 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejnso.2021.212192 | ||||
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Authors | ||||
Mohammed Mahmoud Mohammed Roushdy1; Mahmoud Ragheb Elsherif2; Ezzat Mohamed Saleh Kayed2; Shimaa Farghaly3; Ahmed Ragab Sayed4 | ||||
1Otorhinolaryngology in Otorhinolaryngology department Assiut university hospital, Assiut University, Assiut, Egypt | ||||
2Otorhinolaryngology in Otorhinolaryngology department Assiut university hospital. , Assiut University, Assiut, Egypt | ||||
3Radiodiagnosis in Radio-diagnosis department Assiut university hospital, Assiut University, Assiut, Egypt | ||||
4Otorhinolaryngology department in Assiut university hospital. , Assiut University, Assiut, Egypt | ||||
Abstract | ||||
Background and Purpose: To detect sensitivity and specificity of diffusion-weighted imaging (DWI) as a non-invasive technique in the detection of de-novo cases of cancer larynx Patients and methods: Patients included in this research were patients suspected of de-novo cancer larynx; This study is a prospective randomized comparative clinical trial. Results: The mean apparent diffusion coefficient (ADC) of laryngeal lesions (0.73± SD 0.23 x10-.3 mm2) was lower (p < 0.001) than the mean of the normal part of the larynx in the same patients (1.09± SD 0.099 x 10-.3 mm2), The cut-off value of the ADC using receiver operating characteristics was Conclusion: DWI is an easily reproducible and non-invasive technique that can accurately explore the larynx and became a very important diagnostic tool of laryngeal diseases. This study demonstrated the cut-off point of ADC value for discrimination of malignant lesion is <0.87x 10-.3 mm2/s with restricted diffusion in DWI images. | ||||
Keywords | ||||
Diffusion-weighted imaging; laryngeal cancer; new technology in denovo cancer larynx | ||||
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