Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule
Antar Elhammady, M., Ebrahim, E., Abou Gabal, H., El-Matary, M., Fadl, E. (2021). Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule. EKB Journal Management System, 14(1), 1-10. doi: 10.21608/asjs.2021.212865
Mahmoud Reda Antar Elhammady; Emad Eldin Farid Ebrahim; Hoda Hassan Abou Gabal; Mohamed Mahmoud El-Matary; Ehab Mohammed Ali Fadl. "Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule". EKB Journal Management System, 14, 1, 2021, 1-10. doi: 10.21608/asjs.2021.212865
Antar Elhammady, M., Ebrahim, E., Abou Gabal, H., El-Matary, M., Fadl, E. (2021). 'Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule', EKB Journal Management System, 14(1), pp. 1-10. doi: 10.21608/asjs.2021.212865
Antar Elhammady, M., Ebrahim, E., Abou Gabal, H., El-Matary, M., Fadl, E. Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule. EKB Journal Management System, 2021; 14(1): 1-10. doi: 10.21608/asjs.2021.212865

Comparing Pre-Operative Fine Needle Aspiration Cytology to Paraffin Section Post-Operative for Solitary Thyroid Nodule

Ain Shams Journal of Surgery
Article 1, Volume 14, Issue 1, July 2021, Page 1-10  XML PDF (366.9 K)
Document Type: Original Article
DOI: 10.21608/asjs.2021.212865
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Authors
Mahmoud Reda Antar Elhammady1; Emad Eldin Farid Ebrahim2; Hoda Hassan Abou Gabal3; Mohamed Mahmoud El-Matary4; Ehab Mohammed Ali Fadl4
1General Surgery Resident, General Organization of Teaching Hospitals and Institutes, Egypt
2Professor of General Surgery, Faculty of Medicine, Ain Shams University, Egypt
3Associate Professor of Pathology, Faculty of Medicine, Ain Shams University, Egypt
4Lecturer of General Surgery, Faculty of Medicine, Ain Shams University, Egypt
Abstract
Background: Fine needle aspiration cytology (FNAC) is considered the gold standard diagnostic test for the
diagnosis of thyroid nodules. FNAC is a cost effective procedure that provides specific diagnosis rapidly with
minimal complications. Based on the cytology findings, patients could be followed in cases of benign diagnosis and
subjected to surgery in cases of malignant diagnosis therefore decreasing the rate of unnecessary surgery.
Aim of work: To correlate pre-operative fine needle aspiration cytology (FNAC) to post-operative paraffin section
results in diagnosis of solitary thyroid nodule (STN).
Patients and methods: This is a prospective study, it was performed on 30 patients diagnosed as solitary thyroid
nodule; the results for FNAC and histopathological examination were reviewed, evaluated and correlated.
Results: On FNAC, out of 30 cases there were 19 benign lesions; 17 (56.66%) cases were true negative (TN) and
2 (6.67%) cases were false negative (FN).
There were 11 (36.67%) of undetermined significance or suspicious neoplastic lesions diagnosed by FNAC; 10
(33.33%) cases were true positive (TP) and only one (3.33%) case was false positive (FP). After comparison of
results of FNAC with histopathology, the sensitivity, specificity, accuracy, positive predictive value and negative
predictive value were 83.33%, 94.44%, 90%, 90.91% and 89.47%, respectively.
Conclusion: Fine needle aspiration was a significantly better predictor of malignancy, we recommend this
procedure in the light of other investigations as a primary investigation of thyroid lesions in a patient with solitary
thyroid nodules as it should be advised for exclusion of malignancy.
Keywords
Fine needle aspiration cytology; solitary thyroid nodule; paraffin section
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