A Review of Chalcones: Synthesis, Reactions, and Biological Importance
Mukhtar, S., Morsy, N., Hassan, A., Hafez, T., Hassaneen, H., Saleh, F. (2022). A Review of Chalcones: Synthesis, Reactions, and Biological Importance. EKB Journal Management System, 65(8), 379-395. doi: 10.21608/ejchem.2022.112735.5125
Shorouk S. Mukhtar; Nesrin M. Morsy; Ashraf S. Hassan; Taghrid S. Hafez; Hamdi M. Hassaneen; Fatma M. Saleh. "A Review of Chalcones: Synthesis, Reactions, and Biological Importance". EKB Journal Management System, 65, 8, 2022, 379-395. doi: 10.21608/ejchem.2022.112735.5125
Mukhtar, S., Morsy, N., Hassan, A., Hafez, T., Hassaneen, H., Saleh, F. (2022). 'A Review of Chalcones: Synthesis, Reactions, and Biological Importance', EKB Journal Management System, 65(8), pp. 379-395. doi: 10.21608/ejchem.2022.112735.5125
Mukhtar, S., Morsy, N., Hassan, A., Hafez, T., Hassaneen, H., Saleh, F. A Review of Chalcones: Synthesis, Reactions, and Biological Importance. EKB Journal Management System, 2022; 65(8): 379-395. doi: 10.21608/ejchem.2022.112735.5125

A Review of Chalcones: Synthesis, Reactions, and Biological Importance

Egyptian Journal of Chemistry
Article 35, Volume 65, Issue 8, August 2022, Page 379-395  XML PDF (483 K)
Document Type: Review Articles
DOI: 10.21608/ejchem.2022.112735.5125
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Authors
Shorouk S. Mukhtarorcid 1; Nesrin M. Morsy email orcid 2; Ashraf S. Hassanorcid 3; Taghrid S. Hafezorcid 4; Hamdi M. Hassaneen5; Fatma M. Saleh5
1Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Dokki 12622, Egypt
2Organometallic and Organometalloid Chemistry Department,National Research Centre
3Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622, Cairo, Egypt
4Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622 Cairo, Egypt
5Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt
Abstract
Chalcones are considered an important scaffold in organic compounds. Many of their derivatives have a lot of applications. Therefore, this review was covered some synthesis methods of chalcones such as Claisen-Schmidt’s condensation, coupling reaction, continuous-flow deuteration reaction, and other reactions. Also, some reactions were discussed such as the synthesis of seven, six, and five-membered ring heterocyclic compounds. Moreover, some of their biological applications were mentioned like antimicrobial, anticancer, anti-inflammatory, antioxidants, and others with some details.
Keywords
Chalcones; Synthesis; Reactions; Biological applications
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