Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers | ||||
| The Egyptian Journal of Plastic and Reconstructive Surgery | ||||
| Article 22, Volume 42, Issue 1, January 2018, Page 145-150 PDF (7.42 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejprs.2018.215080 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ayman Farahat* 1; Osama Al Shahat1; Ismaeil Al Khawaga2; Mohamed Ibrahim 3
| ||||
| 1The Department of Plastic Surgery, Faculty of Medicine, Al-Azhar University | ||||
| 2The Department of General Surgery , Faculty of Medicine, Al-Azhar University | ||||
| 3The Departments of Plastic Surgery, Faculty of Medicine, Al-Azhar University | ||||
| Abstract | ||||
| Background: The application of autologous lipo-transfer (fat grafting) in reconstructive surgery becomes more popular now as an evidence for the regenerative effect of fat. In our study we used the autologous lipo-transfer for treatment of chronic ulcers at leg. Methods: Twenty patients with chronic leg ulcers included in our study, ten of them injected with autologous fat (group < br />A), while the other ten patients were on the usual dressings for chronic ulcers (group B), the duration of our study was for six months with patient age in both group range from 15- 50 years with mean age 35.3 years for injected group and 34.1 for the conservative group. Results: Eight of ten chronic leg ulcers (80 percent) that injected with autologus fat healed completely within average of 8 weeks. With only 2 complicated, one complicated by infection while the other with resorption of fat. Only five patients at the conservative group healed within three months. Conclusion: We described in our study a simple technique to improve wound healing in chronic leg ulcers with a background of vascular diseases, diabetic or traumatic accidents where other interventional options to achieve wound healing have failed. | ||||
| Keywords | ||||
| Fat grafting; Chronic leg ulcers | ||||
| References | ||||
|
Gronthos S., Zannettino A.C.W., Hay S.J., Shi S., Graves S.E., Kortesidis A. and Simmons P.J.: Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. Journal of Cell Science, 116: 1827-35, 2003. 2- Kaminer M.S. and Omura N.E.: Autologous fat transplantation. Arch. Dermatol., 137 (6): 812-814, 2001. 3- Christopher E.A., Jeffrey E.J., Steinberg, Schwartz, Ali A. and Kara C.: Clinical Approach to Wounds: Debridement and Wound Bed Preparation Including the Use of Dressings and Wound-Healing Adjuvants. Plastic Reconstructive Surgery, 117 (Suppl.): 72S, 2006. 4- Coleman S.R.: Structural fat grafting: More than permanent filler. Plastic and Reconstructive Surgery, 118: 108-120, 2006. 5- Lin K., Matsubara Y., Masuda Y., et al.: Characterization of adipose tissue-derived cells isolated with the Celution system. Cytotherapy, 10: 417, 2008. 6- Marino G., Moraci M., Armenia E., et al.: Therapy with autologous adipose-derived regenerative cells for the care of chronic ulcer of lower limbs in patients with peripheral arterial disease. J. Surg. Res., 185: 36-44, 2013. 7- F. Caviggioli, D. Forcellini, V. Vinci, G. Cornegliani, F. Klinger and M. Klinger: “Employment of needles: A different technique for fat placement,” Plastic and Reconstructive Surgery, Vol. 130: pp. 373e–374e, 2012. 8- Cervelli V., Gentile P. and Grimaldi M.: Regenerative surgery: Use of fat grafting combined with platelet-rich plasma for chronic lower-extremity ulcers. Aesthetic Plast Surg., 33: 340-345, 2009. 9- Mohan A. and Singh S.: Journal of wound care, Vol. 26, No 5 May 2017. 10- Tilman Stasch, Julius Hoehne, Tuan Huynh Randy De Baerdemaeker, Siegfried Grandel and Christian Herold: Volume 136, Number 6 Débridement and Autologous Lipotransfer by the American Society of Plastic Surgeons, 2015. 11- Bartsich S. and Norman Morrison WOUNDS: 24 (3): 51, Volume 24 - Issue 3 - March 2012. | ||||
|
Statistics Article View: 118 PDF Download: 216 |
||||
