Is Lidocaine better than Magnesium Sulfate as an adjuvant with propofol in Colonoscopy? | ||||
Minia Journal of Medical Research | ||||
Volume 31, Issue 4, October 2020, Page 95-100 PDF (362.29 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.217133 | ||||
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Authors | ||||
Ahmed M. Semeda1; Ibrahim A. Yousef1; Al Shimaa I. Roushdy2 | ||||
1Department of Anesthesia, El-Minia Faculty of Medicine | ||||
2Department of Anesthesia, El-Minia Faculty of Medicin | ||||
Abstract | ||||
Background: Colonoscopy is one of the most commonly performed outpatient procedures throughout the world as a screening, diagnostic, and therapeutic tool. propofol is the most common drug used for sedation during endoscopy either alone or in combination with another agent. Patients and Methods: A total of 90 patients of both gender aged between 18 and 70 years with American Society of Anesthesiologists grade I and II patients scheduled to undergo colonoscopy, under sedation were included in the study. Patients were randomly allocated into 3 equal groups each containing 30 patient. Group (L) received 1.5 mg/ kg of lidocaine IV before induction by propofol and continuous infusion of lidocaine 4 mg kg/ h after induction, group (M) received50 mg/ kg of magnesium sulphate before induction by propofol and continuous infusion of magnesium 8 mg/ kg/h after induction and group (O) as control group received normal saline 0.9% Sodium Chloride. Results: There was a significant difference in intraoperative hemodynamic stability, total amount of propofol, post procedural pain and analgesic demand, and patient between three groups. Conclusion: we concluded that lidocaine infusion by dose 1.5 mg/kg loading and 4 mg/kg/ h as maintenance is more effective than magnesium sulfate by dose 50 mg/kg loading and 8 mg/kg/ h maintenance in decreasing total amount of propofol, post procedural pain and analgesic demand, and improving patient satisfaction in patient undergoing colonoscopy under sedation with propofol. | ||||
Keywords | ||||
PSA; colonoscopy; lidocaine; magnesium | ||||
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