Magnetic resonance imaging of multiple sclerosis | ||||
Minia Journal of Medical Research | ||||
Volume 31, Issue 4, October 2020, Page 172-177 PDF (175.12 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.217922 | ||||
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Authors | ||||
Hosny S. Abd El-Ghany1; Enas A. Abdel Gawad2; Mohamed M. Esmaeel3; Mahmoud M. Moneer2; Alaa W. Fathy2; Ahmed M. Elshafei4; Mohamed F. Othman4; Asmaa A. Mohamed4; Mahmoud E. Rabie4 | ||||
1Department of Radiology, El-Minia Faculty of medicine, El-Minia- Egypt | ||||
2Department of Radiology, El-Minia Faculty of medicine, El-Minia- Egypt. | ||||
3Department of Neurology and Psychiatry, El-Minia Faculty of medicine, El-Minia- Egypt. | ||||
4Department of Ophthalmology, El-Minia Faculty of Medicine | ||||
Abstract | ||||
Background: Magnetic resonance imaging (MRI) has an important role in early diagnosis of MS. Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Patients and Methods: forty patients clinically diagnosed to have MS according to McDonald criteria were included and referred to department of radio-diagnosis, Faculty of Medicine, Minia University. Imaging was performed on a 1.5T Philips MR system using double inversion recovery (DIR), fluid attenuated inversion recovery (FLAIR), T2-weighted, T1-weighted and susceptibility-weighted imaging (SWI) sequences with the parameters including field of view (FOV), matrix, slice thickness and voxel size. They were done after the approval of ethical committee of our institution. Data analysis was performed using the SPSS version 20 and p-value as well as comparative study were gained. Results: The detection rate of white matter lesions in T2 was (80%); while for grey matter lesions was (12%). In FLAIR sequence, we found that; the detection rate of white matter lesions was (97%); while for grey matter lesions was (26%). As regarding DIR sequence, the detection rate of white matter lesions was (93%); while for grey matter lesions was (95%).Comparative study between serial MRI sequences (T2,FLAIR and DIR) revealed; significant increase in detected number of grey matter lesions; in DIR-MRI sequence (p < 0.0001). In SWI, a central vein sign was detected in 97 lesions (66 in periventricular lesions and 31 in subcortical lesions). Conclusion: From this study we concluded that new imaging modalities of MRI as regarding DIR and SWI are a valuable MRI sequences in imaging of multiple sclerosis; thus, we recommend adding DIR and SWI sequences in routine MR protocols for MS patients. | ||||
Keywords | ||||
MRI; multiple sclerosis; Double inversion recovery (DIR); SWI; T2; FLAIR | ||||
Supplementary Files
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