Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations
Abdallah, A., Hammad, M., Sadeq, A., Zaki, ,., Ali, H., Abd-El Hakeem, M. (2020). Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations. EKB Journal Management System, 31(4), 332-337. doi: 10.21608/mjmr.2022.218159
Adel A. Abdallah; Mostafa S. Hammad; Ahmad A. Sadeq; , Zaki Mohamed Zaki; Heballa A. Ali; Mostafa T. Abd-El Hakeem. "Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations". EKB Journal Management System, 31, 4, 2020, 332-337. doi: 10.21608/mjmr.2022.218159
Abdallah, A., Hammad, M., Sadeq, A., Zaki, ,., Ali, H., Abd-El Hakeem, M. (2020). 'Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations', EKB Journal Management System, 31(4), pp. 332-337. doi: 10.21608/mjmr.2022.218159
Abdallah, A., Hammad, M., Sadeq, A., Zaki, ,., Ali, H., Abd-El Hakeem, M. Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations. EKB Journal Management System, 2020; 31(4): 332-337. doi: 10.21608/mjmr.2022.218159

Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations

Minia Journal of Medical Research
Volume 31, Issue 4, October 2020, Page 332-337  XML PDF (337.38 K)
Document Type: Original Article
DOI: 10.21608/mjmr.2022.218159
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Authors
Adel A. Abdallah1; Mostafa S. Hammad1; Ahmad A. Sadeq1; , Zaki Mohamed Zaki2; Heballa A. Ali1; Mostafa T. Abd-El Hakeem1
1Department of Otorhinolaryngology; Faculty of Medicine – Minia University- Egypt
2Department of clinical pathology; Faculty of Medicine – Minia University- Egypt
Abstract
Purpose: A retrospective clinical study for reporting the efficacy of fat grafting for small 
tympanic membrane perforations due to: trauma, infection, post-tympanostomy tube 
extraction and post myringoplasty residual perforations with topical use of autologous platelet 
rich plasma (PRP). Patients and Methods: Thirty patients aged between 18 to 58 years; with 
fat graft myringoplasty were operated for closure of tympanic membrane perforation due to 
the above causes. Half the patients underwent fat graft myringoplasty (group A), while others 
received the fat graft with PRP (group B). Results: The graft was taken in 13 patients 
(86.7%) in group A, and in 14 patients (93.3%) in group B. Healing time was shorter in group 
B (2 months) than in group A (3 months). There was insignificant different between the two 
graft types in hearing gain, but in each graft type there was significant decrease in the mean 
ABG postoperatively. Conclusion: Fat graft myringoplasty is an easy, simple, fast and 
minimally invasive procedure for the repair of small tympanic membrane perforations with 
favorable results with topical autologous PRP.

Keywords
Myringoplasty; Platelet Rich Plasma; tympanic membrane; traumatic perforation;  small and medium sized perforation; fat graft; Chronic Suppurative Otitis Media
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