Preparation of New Complexes of Bivalent Manganese, Iron, Cobalt, and Nickel with Mixed Ligands of Ciprofloxacin (Cip) and Metronidazole (Met) or 4-Aminoantipyrine (4AAP) with Study of Their Chemical, Physical Properties and Antibacterial Activity | ||||
Egyptian Journal of Chemistry | ||||
Article 2, Volume 65, Issue 9, September 2022, Page 11-19 PDF (574.47 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2022.117975.5315 | ||||
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Authors | ||||
samaa adnan raoof 1; waseem M Hasan2; ammar A Aziz1; Shakir Mahmood Saied3; Mohanad Yakdhan Saleh 4 | ||||
1Northern Technical University | ||||
2Al-noor University College | ||||
3Dept. of Medical Laboratories Technique Al-Noor University College, Mosul | ||||
4Department of Chemistry, College of Education for pure science, University of Mosul | ||||
Abstract | ||||
Synthesis of mixed metal complexes were done through reaction of two drugs such as antipyrine, or ciprofloxacin with Metronidazole to have eight complexes. Physical, chemical and antibacterial activity of new complexes were studied. These mixed ligands were further coordinating with bivalent transition metals in a metal: ligands mixture ratio 1:1. These complexes were characterized by using elemental analysis and physical properties, in addition molar conductance in DMF which showed non-electrolytic behavior. FT-IR spectra revealed absorption bands for new ligands and metal complexes that agreed with the propose structures and the electronic spectra verified that these complexes display six-coordinate octahedral geometry. Antibacterial activity showed good results. | ||||
Keywords | ||||
Ciprofloxacin; Metronidazole; 4-Aminoantipyrine; Mixed ligands; Antibacterial Activity | ||||
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