Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease
zordok, S., sadek, Y., abdel aziz, B., behiry, E. (2022). Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease. EKB Journal Management System, 39(1), 123-135. doi: 10.21608/bmfj.2021.73869.1412
shimaa zordok; yehia sadek; badawy abdel aziz; eman behiry. "Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease". EKB Journal Management System, 39, 1, 2022, 123-135. doi: 10.21608/bmfj.2021.73869.1412
zordok, S., sadek, Y., abdel aziz, B., behiry, E. (2022). 'Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease', EKB Journal Management System, 39(1), pp. 123-135. doi: 10.21608/bmfj.2021.73869.1412
zordok, S., sadek, Y., abdel aziz, B., behiry, E. Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease. EKB Journal Management System, 2022; 39(1): 123-135. doi: 10.21608/bmfj.2021.73869.1412

Helicobacter Pylori Infection in Patients with Non Alcholic Fatty Liver Disease

Benha Medical Journal
Article 9, Volume 39, Issue 1, March and April 2022, Page 123-135  XML PDF (574.08 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2021.73869.1412
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Authors
shimaa zordok email 1; yehia sadek2; badawy abdel aziz3; eman behiry4
1Hepatology, Gastroenterology and Infectious Diseases. Faculty of Medicine Benha University
2(Professor of Hepatology, Gastroenterology and Infectious Diseases)
3Assistant Professor of Hepatology, Gastroenterology and Infectious Diseases
4Assistant Professor of Clinical and Chemical Pathology)
Abstract
Background: Although there have been conflicting results, several subsequent clinical trials have demonstrated a higher rate of fatty liver and NASH in H. pylori -positive patients compared to HP-negative patients; in addition, small trials examining the effect of H. pylori eradication have shown improvement in markers of NAFLD activity, further supporting a link between these two conditions.
Aim: This study was conducted to evaluate the relation of H. Pylori infection with Non Alcholic Fatty Liver Disease (NAFLD).
Methods: This study is a case control study carried out at outpatient's clinics of El Mahalla El Aam Hospital from November 2017 till May 2018, Subjects were classified into two groups: One hundred patients with NAFLD who attended outpatient’s clinics of El Mahalla El Aam Hospital, Group (A) (case group): Included 50 patients with NAFLD (diagnosed by ultrasonography). Group (B) (control group): Included 50 subjects (diagnosed by ultrasonography) who will serve as a control group.
Results: There was a statistical significant difference in Hp results between group I and group II groups, with significant Ag positive-Ab positive to Group I, and there was no statistical significant differences in US grades of NAFLD according to HP Ag or Ab results.
Conclusion: Our study was display a significant increase in MPV in patients with NAFLD. The burden of H. Pylori infection among NAFLD patients was noticeably high, in comparison with the healthy control group.
Keywords
Non Alcoholic Fatty Liver Disease; H. pylori; infection; case control
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