TOXICOLOGICAL EFFECT OF LONG TERM ADMINISTRATION OF CERTAIN AGRICULTURAL CONTAMINATES ON ALBINO RATS | ||||
| Journal of Plant Protection and Pathology | ||||
| Article 7, Volume 32, Issue 1, January 2007, Page 681-691 PDF (753.26 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jppp.2007.219412 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| A. A. Saleh1; M. M. Kady1; I. M. El-Nabarawy2; Sh. E. M. Shalby2 | ||||
| 1Pesticides Dept.,Fac.of Agric., Mansoura Univ., | ||||
| 2Pests & Plant Protection Dept., National Research Centre, Dokki, Cairo, Egypt | ||||
| Abstract | ||||
| The objective of this investigation was conducted to study the chronic toxicity of sublethal doses of some very important agriculture chemicals, carbamate nematicide aldicarb ( contains secondary amines), sodium nitrite, sodium nitrate and combination between aldicarb and nitrite or nitrate on some blood content of albino rats. The protective effects of ascorbic acid were studied and the role of sodium chloride to increase the bad effects of previous compounds was also studied. The obtained data revealed that, rats treated with aldicarb followed by nitrite or nitrate caused significant changes (increase or decrease) more than that in case of treated rats each one alone. Addition of sodium chloride to rats which treated by aldicarb followed by nitrite (nitrate) caused more adverse effects on vital hematological and biochemical parameters. On the contrary, ascorbic acid not prevents the toxic effects of the tested chemicals but playing negligible role of recovery when added to aldicarb followed by nitrite or nitrate treated rats. | ||||
| Keywords | ||||
| Aldicarb; N-nitroso compounds - ascorbic acid - sodium chloride; hematological effects; secondary amines | ||||
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