BIOCHEMICAL BIOMARKERS FOR DOSE-DEPENDENT DAMAGE CAUSED BY 4-NONYLPHENOL IN THE JUVENILE CLARIAS GARIEPINUS | ||||
| Assiut University Journal of Multidisciplinary Scientific Research | ||||
| Volume 50, Issue 1, June 2021, Page 23-39 PDF (508.04 K) | ||||
| Document Type: Novel Research Articles | ||||
| DOI: 10.21608/aunj.2021.219959 | ||||
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| Abstract | ||||
| The present study investigates the dose-dependent damage caused by 4-nonylphenol exposure in juvenile of Clarias gariepinus using some biomarkers and the effect of recovery time. Healthy juvenile C. gariepinus of both sexes were classified into four groups (7fish/ group; two replicates). The first one was a control group, and the other three groups were exposed for 15 days to 4-nonylphenol concentrations as 0.1 mg/L, 0.2 mg/L, and 0.3 mg/L respectively, then 15 days as a recovery period after exposure time. The parameters exhibiting significance either increased with the increase of the 4-NP doses from 0.0 in the control to 0.3 mg/L (AST, ALT, TP, Glu, Cr, and UA) or decreased with such increased doses (Alb, and Glo). In conclusion, the liver and kidney functions parameters were indicated the hepatotoxicity and nephrotoxicity of 4-NP and their alterations have decreased to a great extent after a recovery period of 15-days in a reverse order. | ||||
| Keywords | ||||
| 4-nonylphenol; biochemistry | ||||
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