Role of C reactive protein and Erythrocyte sedimentation rate in Obstructive Sleep Apnea | ||||
Minia Journal of Medical Research | ||||
Volume 31, Issue 3, July 2020, Page 172-176 PDF (408.79 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.220255 | ||||
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Authors | ||||
Lamiaa H. Shaaban1; Nezar R. Tawfike2; Zainab H. Saeed1; Hadeer E. Refaat1 | ||||
1Department of Chest Diseases, Faculty of medicine, Minia university, Egypt | ||||
2Department of Chest Diseases, Faculty of medicine, Assuit university, Egypt | ||||
Abstract | ||||
Background: Obstructive sleep apnea ) is a condition characterized by repeated episodes of partial or complete obstruction of the respiratory passages(1) The standard diagnostic procedure for establishing the presence of OSA is the overnight polysomnography(2) . The development of simple, and reliable biomarkers that permit precise screening of at-risk populations is required. So , special interest has centered around potential OSA biomarkers. The ideal biomarker should be highly sensitive , specific and correlate to severity of OSA.(3) Patients and methods: This study was performed on 35clinically suspected OSA patients, and15 non-smoker healthy control persons . Patients were recruited from of Minia cardiothoracic university hospital during the period from September 2018 to September 2019. All patients were assessed for excessive day time sleepiness by Epworth sleepiness score and STOPBANG score, pulmonary function tests (FEV1, FVC and FEV1/FVC)% predicted, ABG, and measurements of C reactive protein (CRP) and Erythrocyte sedimentation rate (ESR) were done for all patients and control. Results: This study were performed on 50 patients 35 cases and 15 control group and showed a Significant elevation in CRP and ESR in the case group compared to the control group. Conclusion: The current study showed that there was a significant elevation in CRP and ESR in case group versus control group. | ||||
Keywords | ||||
OSA; Obstructive sleep apnea; CRP:C-reactive proteinFEV1:Forced expiratory volume at the first second; FVC: Forced Vital Capacity | ||||
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