Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo
Samy, A., El-Sabbagh, A., Mohamed, A., Abdel-Halim, M. (2022). Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo. EKB Journal Management System, 46(1), 9-14. doi: 10.21608/ejprs.2022.220420
Aya Samy; Ahmed El-Sabbagh; Adel Mohamed; Mostafa M. Abdel-Halim. "Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo". EKB Journal Management System, 46, 1, 2022, 9-14. doi: 10.21608/ejprs.2022.220420
Samy, A., El-Sabbagh, A., Mohamed, A., Abdel-Halim, M. (2022). 'Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo', EKB Journal Management System, 46(1), pp. 9-14. doi: 10.21608/ejprs.2022.220420
Samy, A., El-Sabbagh, A., Mohamed, A., Abdel-Halim, M. Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo. EKB Journal Management System, 2022; 46(1): 9-14. doi: 10.21608/ejprs.2022.220420

Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo

The Egyptian Journal of Plastic and Reconstructive Surgery
Article 3, Volume 46, Issue 1, January 2022, Page 9-14  XML PDF (11.87 MB)
Document Type: Original Article
DOI: 10.21608/ejprs.2022.220420
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Authors
Aya Samy email 1; Ahmed El-Sabbagh2; Adel Mohamed3; Mostafa M. Abdel-Halim4
1Plastic surgery department, Mansoura university, Mansoura, Egypt
2The Department of Plastic Surgery, Faculty of Medicine, Mansoura University
3The Department of General Surgery, Faculty of Medicine, Mansoura University
4The Department of Plastic Surgery , Faculty of Medicine, Mansoura University
Abstract
Introduction: Vitiligo is a depigmented common skin
disorder. The disease may lead to social and psychological
distress to the patient. Therefore, a good treatment can improve
the patient's life quality. Punch grafting is a simple and
commonly used method of treating vitiligo. However, it is
time consuming with the risk of post-operative cobble stoning
appearance. We used motorized 0.8-1.3 micro-punch grafting
procedure to overcome these limitations.
Aim: To evaluate the therapeutic effectiveness of using
micro-punch grafting to treat vitiligo and adverse events
associated with this method.
Patients and Methods: This is a prospective study for 20
patients with vitiligo. They underwent motorized 0.8-1.3
micro-punch grafting from 2019 to June 2020.
Results: Thirty percent of the patients showed excellent
re-pigmentation ³75%. Forty percent of the patients showed
moderate re-pigmentation. Twenty percent of the cases showed
mild re-pigmentation and only 10% showed no improvement.
Conclusion: Micro-punch grafting is an effective way to
treat vitiligo; it is also considered a suitable option with
tolerable adverse events.
Keywords
Vitiligo; Resistant cases; Micro-punch grafting
References
1- Mulekar S.V.: Surgical Modalities in Management of
Vitiligo. Pigmentary Skin Disorders, 139-145, 2018.
2- Bae J.M., Lee J.H., Kwon H.S., Kim J. and Kim D.S.:
Motorized 0.8-mm micropunch grafting for refractory
vitiligo: A retrospective study of 230 cases. Journal of
the American Academy of Dermatology, 79 (4): 720-727,
2018.
3- Kovacs D., Bastonini E., Ottaviani M., Cota C., Migliano
E., Dell'Anna M.L. and Picardo M.: Vitiligo skin: Exploring
the dermal compartment. Journal of Investigative
Dermatology, 138 (2): 394-404, 2018.
4- Huggins R.H., Henderson M.D., Mulekar S.V., Ozog
D.M., Kerr H.A., Jabobsen G. and Hamzavi I.H.: Melanocyte-
keratinocyte transplantation procedure in the treatment
of vitiligo: The experience of an academic medical
center in the United States. Journal of the American
Academy of Dermatology, 66 (5): 785-793, 2012.
5- Herskovitz I., Hughes O.B., Macquhae F., Rakosi A. and
Kirsner R.: Epidermal skin grafting. International Wound
Journal, 13 (S3): 52-56, 2016.
6- Bae J.M., Lee J.H., Kwon H.S., Kim J. and Kim D.S.:
Motorized 0.8-mm micropunch grafting for refractory
vitiligo: A retrospective study of 230 cases. Journal of
the American Academy of Dermatology, 79 (4): 720-727,
2018.
7- Babu A., Thappa D.M. and Jaisankar T.J.: Punch grafting
versus suction blister epidermal grafting in the treatment
of stable lip vitiligo. Dermatologic Surgery, 34 (2): 166-
178, 2008.
8- Sachdev M. and Shankar D.K.: Pulsed erbium: YAG laserassisted
autologous epidermal punch grafting in vitiligo.
International Journal of Dermatology, 39 (11): 868-871,
2000.
9- Gupta S. and Kumar B.: Epidermal grafting in vitiligo:
influence of age, site of lesion, and type of disease on
outcome. Journal of the American Academy of Dermatology,
49 (1): 99-104, 2003.
10- Hardman M.J. and Ashcroft G.S.: Estrogen, not intrinsic
aging, is the major regulator of delayed human wound
healing in the elderly. Genome Biology, 9 (5): 1-17, 2008.
11- NATALE C.A., DUPERRET E.K., ZHANG J., SADEGHI
R., DAHAL A., O'BRIEN K.T. and RIDKY T.W.: Sex
steroids regulate skin pigmentation through nonclassical
membrane-bound receptors. Elife, 5: e15104, 2016.
12- Filippova O.V., Afonichev K.A., Krasnogorskiy I.N. and
Vashetko R.V.: Clinical and morphological characteristics
of the vascular bed of hypertrophic scar tissue in different
periods of its formation. Pediatric Traumatology, Orthopaedics
and Reconstructive Surgery, 5 (3): 25-35, 2017.
14 Vol. 46, No. 1 / Usefulness of Micro-Punch Skin Grafting for Treatment of Resistant Vitiligo
13- Lahiri K., Malakar S., Sarma N. and Banerjee U.: Repigmentation
of vitiligo with punch grafting and narrowband
UV-B (311nm) a prospective study. Int. J. Dermatol., 45:
649-55, 2006.
14- Falabella R.: Surgical treatment of vitiligo: Why, when
and how. Journal of the European Academy of Dermatology
and Venereology: JEADV, 17 (5): 518-520, 2003

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