Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).
Ahmed, F., Reda, R. (2021). Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).. EKB Journal Management System, 13(2), 223-238. doi: 10.21608/eajbsz.2021.220560
Farag A. Gh. Ahmed; Rasha M. Reda. "Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).". EKB Journal Management System, 13, 2, 2021, 223-238. doi: 10.21608/eajbsz.2021.220560
Ahmed, F., Reda, R. (2021). 'Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).', EKB Journal Management System, 13(2), pp. 223-238. doi: 10.21608/eajbsz.2021.220560
Ahmed, F., Reda, R. Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).. EKB Journal Management System, 2021; 13(2): 223-238. doi: 10.21608/eajbsz.2021.220560

Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus).

Egyptian Academic Journal of Biological Sciences, B. Zoology
Article 26, Volume 13, Issue 2, December 2021, Page 223-238  XML PDF (926.43 K)
Document Type: Original Article
DOI: 10.21608/eajbsz.2021.220560
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Authors
Farag A. Gh. Ahmed1; Rasha M. Reda2
1Plant Protection Dept., Faculty of Agriculture, Zagazig University, P.O. Box, 44511, Zagazig, Egypt.
2Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Zagazig University, P.O. Box 44511, Zagazig, Egypt.
Abstract
The goal of this study is to assess the acute and sublethal potential hazards on tilapia fish (Oreochromis niloticus) exposed to two different commercial formulations of abamectin (ABM, 5%): emulsifiable concentration (EC) and microemulsions (ME). The median lethal concentration (LC50 - 96 h) to each formulation was determined, as well as the adverse effects of sublethal concentrations (½ LC50) on physiological and oxidative stress biomarkers after 96hs of exposure. The LC50 (96 h) values for EC and ME were 10 and 16.6 µg/L, respectively. Furthermore, in both EC and ME, the findings of physiological and oxidative stress aspects revealed significant markedly increases in serum total protein, albumin, globulin, and urea, as well as a significant decline in aminotransferases activity (ALT and AST), and creatinine levels (Cre). Moreover, superoxide dismutase (SOD), malondialdehyde (MDA), catalase (CAT), and glutathione peroxidase (GPx) were greatly increased, whereas glutathione-S-transferase (GST) and glutathione (GSH) were significantly reduced in the liver and brain. 
Keywords
Abamectin; Formulations; Nile tilapia (Oreochromis niloticus); LC50; liver and kidney function; oxidative stress
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