Lipid response in Hcv patients treated by direct acting antivirals | ||||
Minia Journal of Medical Research | ||||
Volume 31, Issue 2, April 2020, Page 42-45 PDF (340.84 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.220834 | ||||
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Authors | ||||
Hassan M. Mohey El-Din1; Asmaa K. Ahmed1; Shereen G. Samy2; Asmaa A. Mohammed3 | ||||
1Department of Internal Medicin, Faculty of Medicin-Minia Universty | ||||
2Departement of biochemistry, faculty of medicin - Minia university | ||||
3one day surgery hopital- Minia governerat | ||||
Abstract | ||||
Background: sustained virological response (SVR) can be achived in high percentage of HCV patients with the availability of direct acting antiviral agents DAAs. We hypothesize that treatment of HCV with novel direct-acting antiviral may affect lipid profil in diabetic pateints who achieve sustained virological response after DAAs. In our study 50 Chronic HCV patients candidate to Internal Medicine Department and Hepatology unite of One Day Surgery Hospital for treatment with DAAs. Measurement of total cholesterol, HDL, LDL and triglyceride level befor and after DAAs therapy is done. Statistical analysis was done for these data. Results: After SVR; There is highly statistical significant difference as regard each of cholesterol, triglycerides, HDL and LDL, with lower level observed after treatment (p < 0.001). Conclusions: This study shows that eradication of HCV by DAAs will result in a parallel decrease in lipid parameters and that may improve clinical outcomes in patients with stablished T2DM. | ||||
Keywords | ||||
DAAs. Direct acting antiviral; Hepatitis C Virus; lipid profil | ||||
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