Hepatitis E virus infection in patients with acute on top of chronic liver diseases | ||||
| Minia Journal of Medical Research | ||||
| Volume 31, Issue 2, April 2020, Page 108-111 PDF (199.04 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2022.220846 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Magdy Fouad1; Reem Y. El Sheemy2; Shereen S. Gaber3; Randa Sh. Ali4 | ||||
| 1Department of Tropical Medicine, Faculty of Medicine, Minia University | ||||
| 2Department of Tropical Medicine, Faculty of Medicine, Minia University. | ||||
| 3Department of Biochemistry, Faculty of Medicine, Minia University. | ||||
| 4* Department of Tropical Medicine, Faculty of Medicine, Minia University | ||||
| Abstract | ||||
| Introduction: Acute on chronic liver failure (ACLF) characterized mainly by acute deterioration of underlying chronic liver disease. Hepatitis E virus (HEV) was reported as a precipitating event. Aim of the study: The aim of this study was to detect HEV infection in patients with acute on chronic liver failure. Materials & Methods: This is across sectional study conducted in Tropical department Minia university hospital in the period from December 2018 to December 2019. It included 30 patients with acute on chronic liver disorders, where blood samples were collected and HEV tested for anti-IgM and IgG by ELISA and then for HEV RNA by RT-PCR. Results: HEV RNA was detected in 13% of patients and IgG was positive in 26.7% of patients with acute on chronic liver failure. Discussion: HEV infection is a common cause in patients with chronic liver disease and presented with unexplained ACLF. Recommendation: based on the current study we recommend searching for HEV infection in patients with ACLF as one of our workup. | ||||
| Keywords | ||||
| Acute on chronic liver failure; HEV infection | ||||
|
Supplementary Files
|
||||
|
Statistics Article View: 52 PDF Download: 77 |
||||
