Kidney injury molecule-1 as a biomarker for prediction of kidney injury in pre-eclampsia | ||||
| Minia Journal of Medical Research | ||||
| Volume 31, Issue 1, January 2020, Page 251-256 PDF (273.24 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2022.221515 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Ahmed M. Kamel; Mohammed H. Mosabh; Ahmed R. Abd El-Reheim; Ahmed M. Abd El-Ghany | ||||
| Department of Obstetrics & Gynaecology, Faculty of Medicine - Minia University | ||||
| Abstract | ||||
| Background: Preeclampsia has remained a public health threat in both developed and developing countries contributing to maternal and perinatal morbidity and mortality globally, Kidney injury with proteinuria is a characteristic feature of preeclampsia, yet the nature of injury in specific regions of the nephron is incompletely understood Aim and objectives: The aim of the present study is to evaluate the role of kidney injury molecule-1 as a biomarker for predicting kidney injury in preeclampsia, Subjects and methods: This is a case control study was carried out at the department of obstetrics and gynecology, Minia maternity university hospital during the period from September 2018 to March 2019, the study was conducted on 90 patients were be enrolled in to the study and divided into two groups, Results: the results of the study revealed that there is high significant correlation between kidney injury molecule -1and severity of preeclampsia, Conclusion: there is an increase in the urinary level of kidney injury molecule-1 in PE, implicating their possible value as biomarkers of kidney injury, | ||||
| Keywords | ||||
| Biomarkers; Kidney; Injury; Pre-Eclampsia; Molecule -1 | ||||
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