Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience
Roshdy, M., Mohie EL-Din, A., Abou El-Ella, K., Zaghloul, N., Ali, M. (2019). Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience. EKB Journal Management System, 30(4), 301-305. doi: 10.21608/mjmr.2022.221741
Michael R. Roshdy; Abu Bakr M. Mohie EL-Din; Khaled A. Abou El-Ella; Nasser M. Zaghloul; Motassem M. Ali. "Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience". EKB Journal Management System, 30, 4, 2019, 301-305. doi: 10.21608/mjmr.2022.221741
Roshdy, M., Mohie EL-Din, A., Abou El-Ella, K., Zaghloul, N., Ali, M. (2019). 'Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience', EKB Journal Management System, 30(4), pp. 301-305. doi: 10.21608/mjmr.2022.221741
Roshdy, M., Mohie EL-Din, A., Abou El-Ella, K., Zaghloul, N., Ali, M. Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience. EKB Journal Management System, 2019; 30(4): 301-305. doi: 10.21608/mjmr.2022.221741

Predicting Patient Survival after Pancreaticoduodenectomy for Malignancy Based on Histopathological Criteria, Minia University Hospital Experience

Minia Journal of Medical Research
Article 46, Volume 30, Issue 4, October 2019, Page 301-305  XML PDF (237.24 K)
Document Type: Original Article
DOI: 10.21608/mjmr.2022.221741
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Authors
Michael R. Roshdy1; Abu Bakr M. Mohie EL-Din2; Khaled A. Abou El-Ella3; Nasser M. Zaghloul4; Motassem M. Ali2
1Department of General Surgery; Faculty of Medicine-Minia university; Egypt
2Department of general surgery and hepato pancreato biliary surgery, Faculty of MedicineMinia University; Egypt
3Department of hepato pancreato biliary surgery; National liver institute- Menoufiya University; Egypt
4Department of general surgery and laparoscopy; Faculty of Medicine-Minia University; Egypt
Abstract
This study aimed to identify histopathological variables that might contribute to survival, 
mortality of patients, and serious complications after pancreaticoduodenectomy. Patients and 
methods: This is prospective hospital based study that been done on all patients who 
underwent pancreaticoduodenectomy in National Liver Institute and Minia university hospital. 
between the first of January 2015 till the end of December 2016. in the surgical department, 
National Liver Institute, Menoufiya University, and Minia university hospital. Results: We 
found that perineural infiltration and lymphovascular invasion were independently significant 
in multivariate analysis, the effects of combining them in terms of predicting long-term survival 
is very important. Smaller and well-differentiated tumors were associated with significantly 
better patient survival (P < 0.03 and P < 0.01, respectively). Positive lymph nodes were 
associated with reduced survival (P < 0.003). Conclusion: The analyze the histopathological 
parameters influencing long-term patient survival after pancreaticoduodenectomy focusing on 
perineural infiltration and lymphovascular invasion as predictors of long-term survival.

Keywords
Pancreaticoduodenectomy; histopathological; tumours 
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