The combination of Hyaluronidase and Magnesium Sulphate as Adjuvants to Bupivacaine in Ultrasound-Guided Supraclavicular Brachial Plexus Block in Upper Limb Surgeries | ||||
Minia Journal of Medical Research | ||||
Article 48, Volume 30, Issue 4, October 2019, Page 310-316 PDF (367.64 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2022.221744 | ||||
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Authors | ||||
Amany K. Abo Elhusein1; Mamdouh Hassan2; Nagat A. Ali.1 | ||||
1Department of Anaesthesiology, Minia University Hospital, Minia, Egypt | ||||
2Department of Anaesthesiology, Minia University Hospital, Minia, Egypt. | ||||
Abstract | ||||
Background: The aim of this trial was to assess the effect of hyaluronidase and MgSo4 when added in combination to bupivacaine on the onset of sensory and motor block, quality of block and effect on duration of action. Methods: Fourty ASA I, II patients of either sex undergoing upper limb Surgery under ultrasound-guided supraclavicular brachial block were recruited in this in this prospective randomized double blinded controlled study and bottles numbered from 1 to 40 were prepared and divided in to two groups each group containe 20 bottles. The solutions in these bottles contain 30 ml volume. The first group contains a mixture of (28 ml 0.5% bupivacaine and 2 ml 0.9% normal saline). The second group contains a (mixture of 28 ml 0.5%bupivacaine and 2 ml of MgSo4 containing 200 mg mixed with 1000 unit hyaluronidase). Results: The onset of sensory and motor block was faster in group (II) than patients in group (I). Also the duration of sensory and motor block was found to be longer in group (II) than in group (I). Conclusions: Our study demonstrates that the combination of hyaluronidase and MgSo4 with bupivacaine for supraclavicular block decrease the onset for surgical anesthesia and increase the duration of sensory block thus it decrease analgesic requirments without significant complications. | ||||
Keywords | ||||
Anesthetic techniques, regional, brachial plexus; anaesthetics local,bupivacaine; equipment, ultrasound machines; hyaluronidase; MgSo4 | ||||
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