Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital
Mahmoud, A., Ibrahim, N., Fahmy, S., Tohamy, M. (2022). Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital. EKB Journal Management System, 3(1), 210-221. doi: 10.21608/ejmr.2022.221866
Aya Talaat Mahmoud; Nermin Hassan Ibrahim; Sameh Samir Fahmy; Mervat Abdel-Baseer Tohamy. "Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital". EKB Journal Management System, 3, 1, 2022, 210-221. doi: 10.21608/ejmr.2022.221866
Mahmoud, A., Ibrahim, N., Fahmy, S., Tohamy, M. (2022). 'Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital', EKB Journal Management System, 3(1), pp. 210-221. doi: 10.21608/ejmr.2022.221866
Mahmoud, A., Ibrahim, N., Fahmy, S., Tohamy, M. Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital. EKB Journal Management System, 2022; 3(1): 210-221. doi: 10.21608/ejmr.2022.221866

Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital

Egyptian Journal of Medical Research
Article 16, Volume 3, Issue 1, January 2022, Page 210-221  XML PDF (354.54 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2022.221866
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Authors
Aya Talaat Mahmoud1; Nermin Hassan Ibrahim1; Sameh Samir Fahmy2; Mervat Abdel-Baseer Tohamy1
1Medical Microbiology and Immunology department, Faculty of Medicine, Beni-Suef University, Egypt
2Pediatrics department, Faculty of Medicine, Beni-Suef University, Egypt
Abstract
The aim of the present study was to identify the incidence of sepsis among neonates admitted at Beni-Suef University Hospital during the period of the study, to identify different organisms responsible for sepsis and the serum level of CD14 (presepsin) was investigated as a biomarker of sepsis. All neonates suspected with sepsis during the time of the study admitted in neonatal intensive care unit at Beni-Suef University Hospital were screened for sepsis by blood culture and presepsin levels were investigated. The incidence of sepsis was 32.4%. Presepsin marker had a significant role in prediction of presence of sepsis, at a cut off value of 2300 or more of presepsin, it can predict the presence of sepsis with sensitivity of (94.29%), specificity of (88.6%), positive predictive value (89.2%) and negative predictive value (93.9%)
Keywords
Neonatal sepsis; CD14; presepsin
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