Evaluation of the accuracy and precision of glomerular filtration rate based equations for the detection of kidney disease in Egyptian patient with hepatitis C virus-related liver cirrhosis | ||||
| Minia Journal of Medical Research | ||||
| Article 20, Volume 30, Issue 3, July 2019, Page 105-108 PDF (150.8 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2022.221880 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Mona A. Abu El-Makarem; Hesham K. H. Keryakos; Leon A. Ayaad | ||||
| Department of Internal Medicine, El-Minia Faculty of Medicine | ||||
| Abstract | ||||
| Introduction: Chronic liver disease is associated with primary and secondary kidney disease and impacts markedly on survival (Slack et al., 2010). Aim of The work: The study aimed to compared the accuracy of different glomerular filteration rate equations based on creatinine, cystatin C and both valuable tools in the detection of kidney disease in hepatitis C virus (HCV)-cirrhosis Egyptian patients. Patients and Methods: Study Participants: The study was reviewed and approved by the local ethics committee and was conducted in accordance with the Helsinki Declaration. Informed consent was obtained from all participants. Results: A total of 60 patients with hepatitis C virus (HCV) – related liver cirrhosis who met the inclusion criteria and 30 healthy volunteers as a control the group was included in this observational hospital-based, cohort study. Patients and Methods: Study Participants: The study was reviewed and approved by the local ethics committee and was conducted in accordance with the Helsinki Declaration. Informed consent was obtained from all participants. Conclusion: Our study concluded that the most predicting model is CKD-EPI Creatinine - Cystatin C (R2=0.785). | ||||
| Keywords | ||||
| filtration rate; hepatitis C; liver cirrhosis | ||||
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