Comparative study of Some biochemical and Immunological parameters of patients with COVID-19 disease and non-infected people | ||||
Egyptian Journal of Chemistry | ||||
Article 20, Volume 65, Issue 10, October 2022, Page 217-223 PDF (331.2 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2022.113854.5172 | ||||
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Authors | ||||
Hayder T Qaddoori 1; abdullah hassan2; mohammed sachit Al-shoky3; Yaser K. Kalil4; Mustafa Mudhafar5 | ||||
1Institute technical baquba, Middle technical university, dayala | ||||
2chemistry department, college science, diyaia university | ||||
3Al-kut university college, medical laboratory techniques | ||||
4College Alqalam University, Karkuk, Iraq | ||||
5Department of Anesthesia and Intensive Care Techniques, Faculty of AL, Tuff Collage, Karbala, 56001, Iraq | ||||
Abstract | ||||
Abstract: The objective of the present study was to evaluate eight biochemical and Immunological parameters and comparison their level in the infected and non-infected people. The methodology include two parts biochemical assays included aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), urea breath test (UREA), and creatinine, and Immunological parameters included D-dimer, ferritin, interleukin 6 (IL-6), C-Reactive Protein (CRP). The result detected by Cobas e411, Cobas C111 device. Results obtained showed high levels of all parameters of covid-19 patients in comparing with the control group patients, with significant differences (p < 0.05). Receiver operating characteristic (ROC) curve showed a high area under the curve for all parameters Area under the ROC Curve (AUC) for all parameters were 1.000, except Patent Cooperation Treaty (PCT) was 0.796) and show high sensitivity for all parameters (sensitivity for all parameters were 100%, except PCT was 75%). The present study was observed significant correlations among the studied of the parameters. | ||||
Keywords | ||||
Covid-19; liver; kidney; Patients; D-dimer; ferritin | ||||
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