Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen | ||||
| Egyptian Journal of Ear, Nose, Throat and Allied Sciences | ||||
| Article 37, Volume 23, Issue 23, January 2022, Page 1-6 PDF (875.55 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejentas.2021.69389.1339 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Aya Magdy Elhusseiny  1; Amany shalaby2; Hesham Mohamed Taha2; Ossama Ashraf Ahmed3
| ||||
| 1Audiology unit ENT department AinShams university | ||||
| 2Audiology unit ENT department AinShams university | ||||
| 3Internal medicine, Gastroenterology & Hepatology department | ||||
| Abstract | ||||
| Background: Previous Hepatitis C Virus (HCV) antiviral drugs reported to cause ototoxicity. Aim: To detect any possible adverse effects of Sovaldi/ Daklinza regimen related to vestibular & balance functions. Patients and Methods: Vestibular & balance were assessed in a total number of thirty adult HCV patients , ranging from twenty to sixty years old before administration of (Sovaldi/Daklinza) and three months later , using Vestibular office tests (Head shake test, Head thrust test, Fukuda stepping test& one leg stance). Videonystagmography (VNG), Sensory organization test (SOT) of Dynamic posturagraphy. Results: After treatment, all patients had normal vestibular office tests, normal VNG testing except for three patients (10% of the study sample) showed positional nystagmus after treatment that wasn’t present before receiving Sovaldi/Daclinza & normal balance function as demonstrated by SOT of Dynamic posturagraphy, with non-statistical significant difference when comparing before and after treatment findings. Conclusion: Sovaldi/Daklinza regimen used in HCV treatment has no statistically significant effect on vestibular & balance function. | ||||
| Keywords | ||||
| Hepatitis C virus; Sovaldi/Daklinza; Vestibular & Balance | ||||
|
Statistics Article View: 947 PDF Download: 334 |
||||
