Nano-Selenium Effect on Sexual Hormones and Enzymatic Activity in Relation to Sexual Puberty in NZW Rabbits | ||||
Arab Journal of Nuclear Sciences and Applications | ||||
Article 8, Volume 55, Issue 2, April 2022, Page 71-78 PDF (547.43 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ajnsa.2022.90792.1503 | ||||
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Authors | ||||
Sherif Eid 1; Hussein Mostafa El-zaher 2; Afatb Shaukat 3; sana sayed emara 4; Yang Liguo 5 | ||||
1Biological Applications Departement, Nuclear Research Center, Cairo, Egypt | ||||
2Biological Applications Department, Radioisotopes Applications Division, Nuclear Research Centre, Egyptian Atomic Energy Authority, Inshas13759, Cairo, Egypt. | ||||
3Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, Huazhong Agricultural University, Wuhan 430070, China. | ||||
4Biological Applications Department, Radioisotopes Applications Division, Nuclear Research Center, Atomic Energy Authority, Inshas13759, Cairo, Egypt. | ||||
5Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, Huazhong Agricultural University, Wuhan 430070, China | ||||
Abstract | ||||
This study aimed to investigate the impact of selenium nano form (Nano-Se) and sodium selenite (SSe) on sexual hormones and enzymatic activity of New Zealand White (NZW) rabbits at puberty. Thirty-six male rabbits and the same number of females (6-weeks old) were distributed into three groups of 24 animals (12 females and 12 males); the groups injected intramuscularly (i.m.) once a week with distilled-water (4ml) as control, 4 ml of a solution containing 90 µg/kg live body weight of Nano-Se or SSe, respectively, for eight weeks. Serum, testicles, and ovaries were obtained at the end of the experiment. Nano-Se increased (P<0.01) ovarian and serum activities of lipase, amylase, and albumin (alb) concentration, with a decrease (P<0.01) in alkaline phosphatase (ALP) activity. In contrast, it decreased ovarian tissue activity of creatine phosphokinase (CPK) and serum alpha-fetoprotein (AFP) and increased (P<0.01) serum ALP in comparison with control. Nano-Se increased (P<0.01) testicular amylase, lipase, AFP, serum CPK, and alb (an opposite trend observed in SSe treatment), with a decrease (P<0.01) of serum ALP and alb. SSe increased (P<0.01) ovarian amylase, CPK, ALP activities, alb, and serum ALP. However, SSe decreased (P<0.01) blood amylase, lipase (also in ovarian tissue), CPK, and AFP weighed to control. Nano-Se and SSe raised Se concentrations in ovarian and testicular extract compared to control. Estradiol-17β, progesterone, and testosterone increased (P<0.01) due to Nano-Se taking | ||||
Keywords | ||||
Nano-Selenium; Enzymatic-activity; puberty; Rabbits | ||||
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